Pulsatile support using a rotary left ventricular assist device with an electrocardiography-synchronized rotational speed control mode for tracking heart rate variability
In: Journal of Artificial Organs, Jg. 19 (2015-11-25), S. 204-207
Online
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Zugriff:
We previously developed a novel control system for a continuous-flow left ventricular assist device (LVAD), the EVAHEART, and demonstrated that sufficient pulsatility can be created by increasing its rotational speed in the systolic phase (pulsatile mode) in a normal heart animal model. In the present study, we assessed this system in its reliability and ability to follow heart rate variability. We implanted an EVAHEART via left thoracotomy into five goats for the Study for Fixed Heart Rate with ventricular pacing at 80, 100, 120 and 140 beats/min and six goats for the Study for native heart rhythm. We tested three modes: the circuit clamp, the continuous mode and the pulsatile mode. In the pulsatile mode, rotational speed was increased during the initial 35 % of the RR interval by automatic control based on the electrocardiogram. Pulsatility was evaluated by pulse pressure and dP/dt max of aortic pressure. As a result, comparing the pulsatile mode with the continuous mode, the pulse pressure was 28.5 ± 5.7 vs. 20.3 ± 7.9 mmHg, mean dP/dt max was 775.0 ± 230.5 vs 442.4 ± 184.7 mmHg/s at 80 bpm in the study for fixed heart rate, respectively (P
Titel: |
Pulsatile support using a rotary left ventricular assist device with an electrocardiography-synchronized rotational speed control mode for tracking heart rate variability
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Autor/in / Beteiligte Person: | Umeki, Akihide ; Ando, Masahiko ; Kishimoto, Satoru ; Nishimura, Takashi ; Date, Kazuma ; Adachi, Hideo ; Fujii, Yutaka ; Arakawa, Mamoru ; Kyo, Shunei ; Kishimoto, Yuichiro ; Takewa, Yoshiaki ; Tatsumi, Eisuke |
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Zeitschrift: | Journal of Artificial Organs, Jg. 19 (2015-11-25), S. 204-207 |
Veröffentlichung: | Springer Science and Business Media LLC, 2015 |
Medientyp: | unknown |
ISSN: | 1619-0904 (print) ; 1434-7229 (print) |
DOI: | 10.1007/s10047-015-0875-4 |
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