Are elevated serum haemolysis markers a harbinger of adverse events in HeartMate II patients?
In: Interactive CardioVascular and Thoracic Surgery, Jg. 27 (2018-02-12), S. 5-12
Online
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Zugriff:
Objectives: Haemolysis during left ventricular assist device support is associated with thrombosis. In this retrospective study, we analysed whether low-level haemolysis (LLH) as defined by simultaneously elevated lactate dehydrogenase (LDH) and free haemoglobin (fHb) levels had an impact on thromboembolic and bleeding events and on von Willebrand factor levels in HeartMate II patients. Methods: After exclusion of patients with LDH >700 U/l and fHb >40 mg/dl at hospital discharge, 79 HeartMate II patients were included. LDH and fHb levels were measured at discharge and in 3 months interval. von Willebrand factor activity and antigen activity were measured 3 months postoperatively. Outcomes regarding ischaemic stroke (IS), pump thrombosis (PT) and gastrointestinal bleeding were recorded. Patients with LLH (400
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Are elevated serum haemolysis markers a harbinger of adverse events in HeartMate II patients?
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Autor/in / Beteiligte Person: | Mohammad Amen Khattab ; Ann Christina Foldenauer ; Ahmad, Usaama ; Moza, Ajay ; Goetzenich, Andreas ; Schnoering, Heike ; Autschbach, Rüdiger ; Shoaib, Mohamed ; Zayat, Rashad ; Tewarie, L. ; Stoppe, Christian ; Publica |
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Zeitschrift: | Interactive CardioVascular and Thoracic Surgery, Jg. 27 (2018-02-12), S. 5-12 |
Veröffentlichung: | Oxford University Press (OUP), 2018 |
Medientyp: | unknown |
ISSN: | 1569-9285 (print) ; 1569-9293 (print) |
DOI: | 10.1093/icvts/ivy027 |
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