Culotte stenting for coronary bifurcation lesions with 2nd and 3rd generation everolimus-eluting stents: the CELTIC Bifurcation Study
In: EuroIntervention, Jg. 14 (2018-06-01), S. e318- (7S.)
Online
unknown
Zugriff:
Aims The aim of this study was to provide contemporary outcome data for patients with de novo coronary disease and Medina 1,1,1 lesions who were treated with a culotte two-stent technique, and to compare the performance of two modern-generation drug-eluting stent (DES) platforms, the 3-connector XIENCE and the 2-connector SYNERGY. Methods and results Patients with Medina 1,1,1 bifurcation lesions who had disease that was amenable to culotte stenting were randomised 1:1 to treatment with XIENCE or SYNERGY DES. A total of 170 patients were included. Technical success and final kissing balloon inflation occurred in >96% of cases. Major adverse cardiovascular or cerebrovascular events (MACCE: a composite of death, myocardial infarction [MI], cerebrovascular accident [CVA] and target vessel revascularisation [TVR]) occurred in 5.9% of patients by nine months. The primary endpoint was a composite of death, MI, CVA, target vessel failure (TVF), stent thrombosis and binary angiographic restenosis. At nine months, the primary endpoint occurred in 19% of XIENCE patients and 16% of SYNERGY patients (p=0.003 for non-inferiority for platform performance). Conclusions MACCE rates for culotte stenting using contemporary everolimus-eluting DES are low at nine months. The XIENCE and SYNERGY stents demonstrated comparable performance for the primary endpoint.
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Culotte stenting for coronary bifurcation lesions with 2nd and 3rd generation everolimus-eluting stents: the CELTIC Bifurcation Study
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Autor/in / Beteiligte Person: | Simon J Walsh ; Hussein, Hafiz ; Oldroyd, Keith G. ; Mylotte, Darren ; Watkins, Stuart ; Smith, Dave ; Alex J Chase ; Hensey, Mark ; Hanratty, Colm G. ; Hill, Jonathan ; Spratt, James C. ; Thomas W Johnson ; Bogaerts, Kris ; Morice, Marie-Claude ; Mulvihill, Niall T. ; Foley, David P. ; Cruden, Nicholas L. |
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Zeitschrift: | EuroIntervention, Jg. 14 (2018-06-01), S. e318- (7S.) |
Veröffentlichung: | Europa Digital & Publishing, 2018 |
Medientyp: | unknown |
ISSN: | 1969-6213 (print) |
DOI: | 10.4244/eij-d-18-00346 |
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