Long-term clinical outcomes after successful and failed recanalization to native chronic Total occlusion: Insights from the Busan chronic Total occlusion (B-CTO) Registry
In: Cardiovascular revascularization medicine : including molecular interventions, Jg. 17 (2015-10-22), Heft 4
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Zugriff:
Objective To assess hard major adverse clinical events (HMACE) after successful versus failed percutaneous coronary intervention for chronic total occlusion (PCI-CTO). Background There are limited data regarding long-term HMACE risks based on PCI-CTO success. Methods First-time PCI was performed in 438 consecutive patients with 473 target CTO lesions. Patients after procedural success (n = 355; 378 CTO lesions) and failure (n = 83; 95 CTO lesions) were followed for an average 40 months (7–77 months range). We compared HMACE (composite of cardiac death, non-fatal myocardial infarction (MI), and stroke) dependent on the success of PCI. Results The incidence of HMACE was low, with a total of 16 events, and did not differ {6% vs.3.1%, HR = 0.47; CI [0.16–1.35; p = 0.162} dependent on the success of PCI-CTO. There were less cardiac deaths {0.3% vs. 1.2%, RR = 0.22; CI [0.01–3.50];p = 0.283}, non fatal MI {1.1% vs.3.6%, RR = 0.27; CI [0.06–1.22], p = 0.089}, but more strokes {1.7% vs.1.2%, RR = 1.32; CI [0.16–10.99], p = 0.795} after successful PCI-CTO. Conclusions The risks of HMACE after PCI-CTO over long-term follow-up were minimal, and do not depend on the procedure success. This unexpected finding somewhat challenge the aggressive interventional approach, and should be confirmed in the adequately powered randomized trial.
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Long-term clinical outcomes after successful and failed recanalization to native chronic Total occlusion: Insights from the Busan chronic Total occlusion (B-CTO) Registry
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Autor/in / Beteiligte Person: | Jong Sung Park ; Serebruany, Victor L. ; Moo Hyun Kim ; Tae Ho Park ; Young Rak Cho ; Tae Hyung Kim ; Park, Kyungil ; Mitsudo, Kazuaki ; Cai De Jin |
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Zeitschrift: | Cardiovascular revascularization medicine : including molecular interventions, Jg. 17 (2015-10-22), Heft 4 |
Veröffentlichung: | 2015 |
Medientyp: | unknown |
ISSN: | 1878-0938 (print) |
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