Hypoglicemic effect of Leandra lacunosa in normal and alloxan-induced diabetic rats
In: Fitoterapia, Jg. 79 (2008-07-01), S. 356-360
Online
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Zugriff:
Leandra lacunosa, popularly known as "erva-do-jabuti", is used in Brazilian folkloric medicine for the treatment of diabetes mellitus. Based on this traditional indication, the aim of this work was to evaluate the hypoglycemic activity of the hydroalcoholic extract of L. lacunosa aerial parts (LLH) in normal and alloxan-induced diabetic rats. Chromatographic fractionation of LLH was also carried out by several techniques, affording isolation of the following major compounds: ursolic acid (1), kaempferol (2), luteolin (3), and quercetin (4). The oral administration of LLH (500 mg/kg) in normal rats caused a significant reduction of 24.7% (P
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Hypoglicemic effect of Leandra lacunosa in normal and alloxan-induced diabetic rats
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Autor/in / Beteiligte Person: | Lucarini, Rodrigo ; Antônio Eduardo Miller Crotti ; Glenda Marqueti Arantes ; Niege Araçari Jacometti Cardoso Furtado ; Daniele da Silva Ferreira ; Márcio Luis Andrade e Silva ; Wilson Roberto Cunha ; AA Da Silva Filho ; Araújo, A.R.B. |
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Zeitschrift: | Fitoterapia, Jg. 79 (2008-07-01), S. 356-360 |
Veröffentlichung: | Elsevier BV, 2008 |
Medientyp: | unknown |
ISSN: | 0367-326X (print) |
DOI: | 10.1016/j.fitote.2008.04.002 |
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