Micronodular thymoma with lymphoid stroma: an immunohistochemical study of the distribution of Langerhans cells and mature dendritic cells in six patients
In: Histopathology, Jg. 66 (2014-11-13), S. 300-307
Online
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Zugriff:
Aims Micronodular thymoma with lymphoid stroma (MNT) is an uncommon variant of thymoma, characterized by multiple small nodules consisting of type A thymoma-like cells, which are separated by abundant B lymphocytes. The aim of the study was to elucidate the pathogenesis of the stromal lymphoid hyperplasia, which is currently unclear. Methods and results We retrieved six cases of MNT, and immunohistochemically examined the number and distribution of Langerhans cells (LCs) and mature dendritic cells (DCs), and compared them with those in type A and type AB thymomas. Many LCs were present within the small tumour nests, but LCs were rarely seen in the stroma (75.5/HPF versus 6.1/HPF, P
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Micronodular thymoma with lymphoid stroma: an immunohistochemical study of the distribution of Langerhans cells and mature dendritic cells in six patients
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| Autor/in / Beteiligte Person: | Tateyama, Hisashi ; Megumi, Yoshida ; Yokoi, Kohei ; Fukui, Takayuki ; Nakamura, Shota ; Taniguchi, Tetsuo ; Takami, Koji ; Kawaguchi, Koji ; Ishikawa, Yoshinori ; Usami, Noriyasu ; Ishiguro, Futoshi ; Matsuguma, Haruhisa |
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| Zeitschrift: | Histopathology, Jg. 66 (2014-11-13), S. 300-307 |
| Veröffentlichung: | Wiley, 2014 |
| Medientyp: | unknown |
| ISSN: | 0309-0167 (print) |
| DOI: | 10.1111/his.12428 |
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