Characterization of a Long Terminal Repeat Region from an Infectious Indian HIV Type 2 Isolate
In: AIDS Research and Human Retroviruses, Jg. 21 (2005-06-01), S. 592-596
Online
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Zugriff:
An infectious Indian human immunodeficiency virus type 2 isolate from Mumbai, propagated in this laboratory, was found to bear an unusually short long terminal repeat (LTR) region. Complete sequencing of the 601 bp LTR indicated a loss of around 250 nucleotide pairs from the unique 3' (U3) region as compared to other well-characterized HIV-2 isolates. Phylogenetic analysis of this LTR shows closest relatedness to the Guinea-Bissau subtype A isolates HIV-2(CAM2) and HIV-2(ALI). The LTR from the biologically active infectious clone with the observed deletion contained all functionally relevant promoter and polyadenylation sequences.
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Characterization of a Long Terminal Repeat Region from an Infectious Indian HIV Type 2 Isolate
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Autor/in / Beteiligte Person: | Tamhane, Mayur C. ; Mukhopadhyaya, Rita ; Mukhopadhyaya, Robin |
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Zeitschrift: | AIDS Research and Human Retroviruses, Jg. 21 (2005-06-01), S. 592-596 |
Veröffentlichung: | Mary Ann Liebert Inc, 2005 |
Medientyp: | unknown |
ISSN: | 1931-8405 (print) ; 0889-2229 (print) |
DOI: | 10.1089/aid.2005.21.592 |
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