Repeatability of Spectral Domain Optical Coherence Tomography Measurements in High Myopia
In: Journal of Glaucoma, Jg. 25 (2016-05-01), S. e526- (5S.)
Online
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Zugriff:
PURPOSE The purpose of this study was to compare the repeatability of spectral domain optical coherence tomography (SDOCT) parameters in high-myopic and emmetropic healthy subjects, and to evaluate the influence of axial length on the repeatability of SDOCT parameters in high myopia. METHODS In a prospective study, 93 eyes of 63 high-myopic subjects (spherical refractive error, -6 to -12 D; median age, 25 y) and 28 eyes of 14 emmetropic (spherical refractive error, 0 D; median age, 30 y) subjects underwent optic nerve head, retinal nerve fiber layer (RNFL), and ganglion cell complex imaging with SDOCT. For the repeatability analysis, 31 eyes of 31 high-myopic subjects and 14 eyes of 14 emmetropic subjects underwent 3 repeated scans in the same session. RESULTS Among the optic nerve head parameters, within-subject coefficient of variation (CVw) measurements of the disc area (0.6% vs. 0.2%), rim area (8.7 vs. 2.8), and rim volume (16.7 vs. 8.9) were significantly larger (worse) in high-myopic compared with the emmetropic subjects. CVw measurements of all RNFL (range, 1.7 to 22.4) and ganglion cell complex (range, 1.8 to 2.5) parameters in high-myopic subjects were comparable to that in emmetropic subjects (2.4 to 24.0 and 1.7 to 2.0, respectively). Axial length significantly affected the CVw of nasal (coefficient, 0.01; P=0.04) and average RNFL (coefficient, 0.004; P=0.001) parameters but not that of the other SDOCT parameters. CONCLUSIONS Repeatabilities of most of the SDOCT parameters in high-myopic subjects were good and comparable to that of emmetropic subjects. This suggests that SDOCT can be useful for following up high-myopic glaucoma patients to detect progression.
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Repeatability of Spectral Domain Optical Coherence Tomography Measurements in High Myopia
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Autor/in / Beteiligte Person: | Bonala, Sampath R. ; Lakshmi, Bodduluri ; Kumar, Addepalli U. ; Yogesh, Kadam ; Rao, Harsha L. |
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Zeitschrift: | Journal of Glaucoma, Jg. 25 (2016-05-01), S. e526- (5S.) |
Veröffentlichung: | Ovid Technologies (Wolters Kluwer Health), 2016 |
Medientyp: | unknown |
ISSN: | 1057-0829 (print) |
DOI: | 10.1097/ijg.0000000000000385 |
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