Pharmacological treatment of asthma in a cohort of adults during a 20-year period : results from the European Community Respiratory Health Survey I, II and III
In: ERJ Open Res. 5:00073-2018 (2019) European Respiratory Journal Open Research (ERJ Open Research), Jg. 5 (2019), Heft 1
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Zugriff:
Asthma often remains uncontrolled, despite the fact that the pharmacological treatment has undergone large changes. We studied changes in the treatment of asthma over a 20-year period and identified factors associated with the regular use of inhaled corticosteroid (ICS) treatment. Changes in the use of medication were determined in 4617 randomly selected subjects, while changes in adults with persistent asthma were analysed in 369 participants. The study compares data from three surveys in 24 centres in 11 countries. The use of ICSs increased from 1.7% to 5.9% in the general population and the regular use of ICSs increased from 19% to 34% among persistent asthmatic subjects. The proportion of asthmatic subjects reporting asthma attacks in the last 12 months decreased, while the proportion that had seen a doctor in the last 12 months remained unchanged (42%). Subjects with asthma who had experienced attacks or had seen a doctor were more likely to use ICSs on a regular basis. Although ICS use has increased, only one-third of subjects with persistent asthma take ICSs on a regular basis. Less than half had seen a doctor during the last year. This indicates that underuse of ICSs and lack of regular healthcare contacts remains a problem in the management of asthma.
Despite increased ICS use, only 34% of subjects with persistent asthma take ICSs on a regular basis
| Titel: |
Pharmacological treatment of asthma in a cohort of adults during a 20-year period : results from the European Community Respiratory Health Survey I, II and III
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| Autor/in / Beteiligte Person: | Janson, Christer ; Accordini, Simone ; Cazzoletti, Lucia ; Cerveri, Isa ; Chanoine, Sebastien ; Corsico, Angelo ; Diogenes Seraphim Ferreira ; Garcia-Aymerich, Judith ; Gislason, David ; Nielsen, Rune ; Johannessen, Ane ; Jogi, Rain ; Malinovschi, Andrei ; Jesús Martinez-Moratalla Rovira ; Marcon, Alessandro ; Pin, Isabelle ; Quint, Jennifer ; Siroux, Valerie ; Almar, Enrique ; Bellisario, Valeria ; Franklin, Karl A. ; Gullón, José A. ; Holm, Mathias ; Heinrich, Joachim ; Nowak, Dennis ; José Luis Sánchez-Ramos ; Weyler, Joost J. ; Jarvis, Deborah ; The members of the ECRHS I scientific team. ; Burney, P. ; Chinn, S. ; Luczynska, C. ; Jarvis, D. ; Lai, E. ; Vermeire, P. ; Kesteloot, H. ; Bousquet, J. ; Nowak, D. ; Prichard, J. ; R. de Marco ; Rijcken, B. ; Anto, J.M. ; Sunyer, J. ; Alves, J. ; Boman, G. ; Nielsen, N. ; Paoletti, P. ; Abramson, M. ; Kutin, J. ; F. van Bastelaer ; Jõgi, R. ; Taytard, A. ; Pin, I. ; Pison, C. ; Neukirch, F. ; Liard, R. ; Knani, J. ; Wichmann, H-E. ; Heinrich, J. ; Magnussen, H. ; Gislason, T. ; Gislason, D. ; Marinoni, A. ; Cerveri, I. ; Bugiani, M. ; Bucca, C. ; Romano, C. ; Cascio, L. ; Campello, C. ; Droste, J. ; Kerkhof, M. ; Gulsvik, A. ; Omenaas, E. ; Martinez-Moratalla, J. ; Almar, E. ; Mateos, A. ; Arévalo, M. ; Sánchez, A. ; Vizcaya, M. ; Aguilar, X. ; Teixidó, A. ; Antó, J.M. ; Kogevinas, M. ; Burgos, F. ; Castellsagué, J. ; Roca, J. ; Soriano, JB. ; Tobías, A. ; Muiñozguren, N. ; J. Ramos González ; Capelastegui, A. ; J. Maldonado Pérez ; Pereira, A. ; Sánchez, J. ; Quiros, J. ; Huerta, I. ; Payo, F. ; Lindholm, N. ; Plaschke, P. ; Janson, C. ; Björnsson, E. ; Rosenhall, L. ; Norrman, E. ; Lundbäck, B. ; Ackermann-Liebrich, U. ; Küenzli, N. ; Perruchoud, A. ; Burr, M. ; Layzell, J. ; Hall, R. ; Harrison, B. ; The members of the ECRHS II scientific team. ; Knox, J. ; Wjst, M. ; Kuenzli, N. ; Walters, E.H. ; Raven, J. ; Weyler, J. ; M. van Sprundel ; Nelen, V. ; Soon, A. ; Raherison, C. ; Ferran-Quentin, J. ; Leynaert, B. ; Zureik, M. ; Bousquet, P.J. ; Frye, C. ; Meyer, I. ; Bjornsson, E. ; Jörundsdóttir, K.B. ; Villani, S. ; Ponzio, M. ; Frigerio, F. ; Comelli, M. ; Grassi, M. ; Corsico, A. ; Bono, R. ; Piccioni, P. ; Caria, E. ; Carosso, A. ; Migliore, E. ; Castiglioni, G. ; Verlato, G. ; Zanolin, E. ; Accordini, S. ; Poli, A. ; V. Lo Cascio ; Ferrari, M. ; Cazzoletti, I. ; Svanes, C. ; Laerum, B. ; J. Martinez-Moratalla Rovira ; Boix, C. ; González, G. ; J.M. Ignacio García ; Solera, J. ; Damián, J. ; Zock, J.P. ; Basagaña, X. ; Jaen, A. ; Acosta, C. ; Muñozguren, N. ; Ramos, J. ; Urrutia, I. ; Aguirre, U. ; Maldonado, J. ; Sanchez, J.L. ; A. de la Vega ; Palenciano, L. ; Azofra, J. ; Cañada, A. ; Toren, K. ; Lillienberg, L. ; Olin, A.C. ; Balder, B. ; Pfeifer-Nilsson, A. ; Sundberg, R. ; Norback, D. ; Wieslander, G. ; Gunnbjornsdottir, M. ; Soderberg, M. ; Franklin, K.A. ; Lundback, B. ; Forsberg, B. ; Nystrom, L. ; Dibbert, B. ; Hazenkamp, M. ; Brutsche, M. ; Seaton, D. ; The members of the ECRHS III scientific team. ; Tumilty, M. ; Potts, J. ; Gislasson, T. ; Rochat, T. ; Leyneart, B. ; Benke, G. ; Dharmage, S. ; Thompson, B. ; Kaushik, S. ; Matheson, M. ; Bentouhami, H. ; Orru, H. ; Girodet, P.O. ; Siroux, V. ; Ferran, J. ; Cracowski, J.L. ; Demoly, P. ; Bourdin, A. ; Vachier, I. ; Soussan, D. ; Courbon, D. ; Neukirch, C. ; Alavoine, L. ; Duval, X. ; Poirier, I. ; Becker, E. ; Woelke, G. ; Manuwald, O. ; Kirsten, A-M. ; Benediktsdottir, B. ; Arnardottir, E.S. ; Clausen, M. ; Gudmundsson, G. ; Gudmundsdottir, L. ; Palsdottir, H. ; Olafsdottir, K. ; Sigmundsdottir, S. ; Bara-Jörundsdottir, K. ; Grosso, A. ; Albicini, F. ; Gini, E. ; E.M. Di Vincenzo ; Ronzoni, V. ; Campanella, F. ; Gnesi, M. ; Manzoni, F. ; Rossi, L. ; Ferraro, O. ; Tassinari, R. ; Bellisario, V. ; Trucco, G. ; Calciano, L. ; Cazzoletti, L. ; A.M. Fratta Pasini ; Locatelli, F. ; Marchetti, P. ; Marcon, A. ; Montoli, E. ; Nguyen, G. ; Olivieri, M. ; Papadopoulou, C. ; Posenato, C. ; Pesce, G. ; Vallerio, P. ; Boezen, H.M. ; Johannessen, A. ; Skorge, T. ; F. Gomez Real ; García, S. ; Núñez, A. ; López, P. ; Sánchez, R. ; Mancebo, E. ; Antó, J-M. ; Garcia-Aymerich, J. ; Carsin, A.E. ; Sanjuas, C. ; Guerra, S. ; Jacquemin, B. ; P. Davdand Galdakao ; Pascual, S. ; J. Antonio Maldonado ; Sánchez, J.L. ; Palacios, L. ; Sánchez, N. ; Fernández, M. ; Robles, B. ; Torén, K. ; Holm, M. ; Kim, J-L. ; Olin, A-C. ; Dahlman-Höglund, A. ; Braback, L. ; Modig, L. ; Järvholm, B. ; Bertilsson, K.A. ; Franklin, H. ; Wahlgreen, C. ; Andersson, B. ; U. Spetz Nystrom ; G.M. Bodinaa Lund ; Nisser, K. ; Probst-Hensch, N.M. ; Künzli, N. ; Stolz, D. ; Schindler, C. ; Gaspoz, J.M. ; E. Zemp Stutz ; Adam, M. ; Autenrieth, C. ; Curjuric, I. ; Dratva, J. ; A. Di Pasquale ; Ducret-Stich, R. ; Fischer, E. ; Grize, L. ; Hensel, A. ; Keidel, D. ; Kumar, A. ; Imboden, M. ; Maire, N. ; Mehta, A. ; Phuleria, H. ; Ragettli, M. ; Ritter, M. ; Schaffner, E. ; Thun, G.A. ; Ineichen, A. ; Schikowski, T. ; Tarantino, M. ; Tsai, M. ; Kapur, S. ; Newson, R. ; Innes, N. ; Wilson, A. ; University, Uppsala ; National Heart and Lung Institute [London] (NHLI) ; Royal Brompton and Harefield NHS Foundation Trust-Imperial College London ; University of Verona (UNIVR) ; University of Pavia ; Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB) ; Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]) ; Monash University [Melbourne] ; Universidade Federal do Parana [Curitiba] (UFPR) ; Universidade Federal do Paraná (UFPR) ; Instituto de Salud Global - Institute For Global Health [Barcelona] (ISGlobal) ; Universitat Pompeu Fabra [Barcelona] (UPF) ; CIBER de Epidemiología y Salud Pública (CIBERESP) ; Landspitali National University Hospital of Iceland ; Haukeland University Hospital ; University of Bergen (UiB) ; Tartu University Hospital [Tartu, Estonia] ; Complejo Hospitalario Universitario de Albacete ; University of Castilla-La Mancha (UCLM) ; Service de chirurgie pédiatrique [CHU Grenoble] ; Centre Hospitalier Universitaire [Grenoble] (CHU) ; Université Grenoble Alpes (UGA) ; Service of the Health Delegation of Albacete [Albacete, Spain] ; University of Turin ; University, Umeå ; Universidad Nacional de San Agustín (UNSA) ; University of Gothenburg (GU) ; Ludwig Maximilian University [Munich] (LMU) ; Helmholtz-Zentrum München (HZM) ; Melbourne School of Population and Global Health [Melbourne] ; University of Melbourne ; German Center for Lung Research - DZL [Munich, Germany] ; Universidad de Huelva ; University of Antwerp (UA) ; Medical Research Council (MRC) ; Imperial College London-Royal Brompton and Harefield NHS Foundation Trust ; Università degli studi di Verona = University of Verona (UNIVR) ; Università degli Studi di Pavia = University of Pavia (UNIPV) ; Universidad de Castilla-La Mancha = University of Castilla-La Mancha (UCLM) ; Università degli studi di Torino = University of Turin (UNITO) ; Helmholtz Zentrum München = German Research Center for Environmental Health ; Siroux, Valérie |
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| Zeitschrift: | ERJ Open Res. 5:00073-2018 (2019) European Respiratory Journal Open Research (ERJ Open Research), Jg. 5 (2019), Heft 1 |
| Veröffentlichung: | Umeå universitet, Kirurgi, 2019 |
| Medientyp: | unknown |
| ISSN: | 2312-0541 (print) |
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