Rescue policy for discarded liver grafts: a single-centre experience of transplanting livers ‘that nobody wants’
In: HPB, Jg. 12 (2010-10-01), Heft 8, S. 523-530
Online
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Zugriff:
hpb_193 523..530 Background: There is a worldwide need to expand the donor liver pool. We report a consecutive series of elective candidates for liver transplantation (LT) who received 'livers that nobody wants' (LNWs) in Argentina. Methods: Between 2006 and 2009, outcomes for patients who received LNWs were analysed and compared with outcomes for a control group. To be defined as an LNW, an organ is required to fulfil two criteria. Firstly, each liver must be officially offered and refused more than 30 times; secondly, the liver must be refused by at least 50% of the LT programmes in our country before our programme can accept it. Principal endpoints were primary graft non-function (PNF), mortality, and graft and patient survival. Results: We transplanted 26 LNWs that had been discarded by a median of 12 centres. A total of 2666 reasons for refusal had been registered. These included poor donor status (n = 1980), followed by LT centre (n = 398) or recipient (n = 288) conditions. Incidences of PNF (3.8% vs. 4.0%), in-hospital mortality (3.8% vs. 8.0%), 1-year patient (84% vs. 84%) and graft (84% vs. 80%) survival were equal in the LNW and control groups. Conclusions: Transplantable livers are unnecessarily discarded by the transplant community. External and internal supervision of the activity of each LT programme is urgently needed to guarantee high standards of excellence.
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Rescue policy for discarded liver grafts: a single-centre experience of transplanting livers ‘that nobody wants’
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Autor/in / Beteiligte Person: | María Martha Ríos ; Osatnik, Javier ; Capitanich, Pablo ; Norberto A Mezzadri ; Mastai, Ricardo ; McCormack, Lucas ; Goldaracena, Nicolas ; Comignani, Pablo ; Anders, Margarita ; Javier Kerman Cabo ; Quiñonez, Emilio |
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Zeitschrift: | HPB, Jg. 12 (2010-10-01), Heft 8, S. 523-530 |
Veröffentlichung: | Elsevier BV, 2010 |
Medientyp: | unknown |
ISSN: | 1365-182X (print) |
DOI: | 10.1111/j.1477-2574.2010.00193.x |
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