Long-term improvement of breast cancer survivors’ quality of life by a 2-week group physical and educational intervention: 5-year update of the ‘PACThe’ trial
In: British Journal of Cancer British Journal of Cancer, Cancer Research UK, 2017, 116 (11), pp.1389-1393. ⟨10.1038/bjc.2017.112⟩; (2017-04-20)
Online
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Zugriff:
The trial was financed by AFRETH (French association for hydrothermal research). Auvergne Regional Council, Clermont-Communauté, League Against Cancer (Puy de Dôme committee CD63).; International audience; Background: The advantages of adapted physical activity and nutritional education (APANE) on breast cancer prognosis and quality of life (QoL) are well known, but long-term results are lacking.Methods: A randomised controlled trial testing a 2-week intervention in hydrothermal centres including APANE enrolled 251 patients ost-chemotherapy. QoL and weight control were significantly improved at 12 months. A 5-year follow-up was performed to evaluate the persistence of improvements.Results: QoL increase (SF36) was persistent: effect-size at 2, 3, 4 and 5 years equalled respectively 0.27 (-0.01; 0.56), 0.28 (-0.02; 0.58),0.41 (0.02; 0.81) and 0.45 (0.11; 0.80).Weight control observed after intervention lasted 2 years: 2.7% decrease at 1 year (P=0.0085), 2.5%at 2 years (P=0.025); and respectively for waist -2.4% (-3.6; -1.1) (P=0.000014) and -1.3% (-2.5; -0.1) (P=0.0072).Conclusions: A 2-week intervention in hydrothermal centres performed shortly after chemotherapy can durably improve breast cancer patients’ QoL and reduce weight.
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Long-term improvement of breast cancer survivors’ quality of life by a 2-week group physical and educational intervention: 5-year update of the ‘PACThe’ trial
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| Autor/in / Beteiligte Person: | Christian François Roques ; Duclos, Martine ; Isabelle Van Praagh-Doreau ; Bignon, Yves-Jean ; Jouvency, Sylvie ; Mouret-Reynier, Marie-Ange ; Vasson, Marie-Paule ; Kwiatkowski, Fabrice ; Hanh, Thierry ; Travade, Armelle ; Bridon, François ; service de recherche clinique ; Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne ; Imagerie Moléculaire et Stratégies Théranostiques - Clermont Auvergne (IMoST) ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne (UCA) ; Unité de Nutrition Humaine (UNH) ; Clermont Université-Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Recherche Agronomique (INRA) ; Unité de Nutrition Humaine - Clermont Auvergne (UNH) ; Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne (UCA) ; d'Oncogénétique, Département ; Institut National de la Recherche Agronomique (INRA)-Réseau National Alimentation Cancer Recherche (réseau NACRe)-Centre Jean Perrin (CJP-EA 4233) ; Centre Jean Perrin [Clermont-Ferrand] (UNICANCER/CJP) ; UNICANCER-UNICANCER ; Imagerie Moléculaire et Stratégies Théranostiques (IMoST) ; Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de la Santé et de la Recherche Médicale (INSERM) ; Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]) ; Institut National de la Recherche Agronomique (INRA)-Réseau National Alimentation Cancer Recherche (réseau NACRe)-Centre Jean Perrin [Clermont-Ferrand] (UNICANCER/CJP) ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]) ; UNICANCER-UNICANCER-Institut National de la Recherche Agronomique (INRA)-Réseau National Alimentation Cancer Recherche (réseau NACRe) |
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| Quelle: | British Journal of Cancer British Journal of Cancer, Cancer Research UK, 2017, 116 (11), pp.1389-1393. ⟨10.1038/bjc.2017.112⟩; (2017-04-20) |
| Veröffentlichung: | HAL CCSD, 2017 |
| Medientyp: | unknown |
| ISSN: | 0007-0920 (print) ; 1532-1827 (print) |
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