Comprehensive Genome Analysis of Carbapenem-Resistant Strains of Raoultella Species, an Emerging Multidrug-Resistant Bacterium in Hospitals
In: Antimicrobial Agents and Chemotherapy, Jg. 63 (2019-12-01)
Online
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Zugriff:
We report the characterization of six carbapenem-resistant Raoultella spp. (CRRS) in our hospital and a genomic analysis of 58 publicly available isolates. CRRS isolates are sporadically identified around the world, and different transposons carrying carbapenemases were the resistant mechanisms. Mobile genetic elements play an important role in acquiring antibiotic resistance genes from the hospital.
We report the characterization of six carbapenem-resistant Raoultella spp. (CRRS) in our hospital and a genomic analysis of 58 publicly available isolates. CRRS isolates are sporadically identified around the world, and different transposons carrying carbapenemases were the resistant mechanisms. Mobile genetic elements play an important role in acquiring antibiotic resistance genes from the hospital. An improved understanding of these transposon and targeted control measures will be very valuable to prevent CRRS dissemination.
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Comprehensive Genome Analysis of Carbapenem-Resistant Strains of Raoultella Species, an Emerging Multidrug-Resistant Bacterium in Hospitals
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Autor/in / Beteiligte Person: | Xiao, Tingting ; Xiao, Yonghong ; Zhu, Yunying ; Zhang, Jing ; Zhou, Yanzi ; Zhang, Shuntian ; Zheng, Beiwen ; Yu, Xiao ; Xu, Hao ; Wang, Yuan |
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Zeitschrift: | Antimicrobial Agents and Chemotherapy, Jg. 63 (2019-12-01) |
Veröffentlichung: | American Society for Microbiology, 2019 |
Medientyp: | unknown |
ISSN: | 1098-6596 (print) ; 0066-4804 (print) |
DOI: | 10.1128/aac.01367-19 |
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