Hypoxia-induced plasticity in the metabolic response of a widespread cichlid
In: Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology, Jg. 166 (2013-05-02), Heft 2
Online
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Zugriff:
The African cichlid, Pseudocrenilabrus multicolor victoriae is a eurytopic fish that exhibits high levels of developmental plasticity in response to dissolved oxygen availability. In this study, F 1 offspring from three sites in the Mpanga River drainage of Western Uganda characterized by different dissolved oxygen (D.O.) regimes were reared under normoxic or hypoxic conditions. After 1 year, enzymes were measured to determine the tissue metabolic capacity of four different tissues: muscle, heart, brain and liver. The enzymes measured were pyruvate kinase [PK], lactate dehydrogenase [LDH], citrate synthase [CS], and cytochrome C oxidase [CCO], and an additional two, malate dehydrogenase (MDH) and fructose 1,6-bisphosphatase (FBPase), were examined in the liver only. Individuals reared under hypoxia exhibited elevated levels of LDH and CCO in the heart; and depressed activity levels of brain CS and liver CCO and MDH relative to normoxia-reared sibs. Results from this study demonstrate that long-term exposure to hypoxia during development can induce changes in the metabolic capacities of P. multicolor . This flexibility may be important in facilitating persistence in variable and/or novel environments, and in the face of increasing global hypoxia.
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Hypoxia-induced plasticity in the metabolic response of a widespread cichlid
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Autor/in / Beteiligte Person: | Chapman, Lauren J. ; Martínez, Mery L. ; Crocker, Cindy D. |
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Zeitschrift: | Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology, Jg. 166 (2013-05-02), Heft 2 |
Veröffentlichung: | 2013 |
Medientyp: | unknown |
ISSN: | 1879-1107 (print) |
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