Effect of bore fluid composition on microstructure and performance of a microporous hollow fibre membrane as a cation-exchange substrate
In: Journal of Chromatography A, Jg. 1394 (2015-05-01), S. 148-153
Online
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Zugriff:
Micro-capillary film (MCF) membranes are effective platforms for bioseparations and viable alternatives to established packed bed and membrane substrates at the analytical and preparative chromatography scales. Single hollow fibre (HF) MCF membranes with varied microstructures were produced in order to evaluate the effect of the bore fluid composition used during hollow fibre extrusion on their structure and performance as cation-exchange adsorbers. Hollow fibres were fabricated from ethylene-vinyl alcohol (EVOH) copolymer through solution extrusion followed by nonsolvent induced phase separation (NIPS) using bore fluids of differing composition (100wt.% N-methyl-2-pyrrolidone (NMP), 100wt.% glycerol, 100wt.% water). All HFs displayed highly microporous and mesoporous microstructures, with distinct regions of pore size
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Effect of bore fluid composition on microstructure and performance of a microporous hollow fibre membrane as a cation-exchange substrate
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Autor/in / Beteiligte Person: | Mandal, Ipshita ; Radu Alexandru Lazar ; Nigel K.H. Slater |
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Zeitschrift: | Journal of Chromatography A, Jg. 1394 (2015-05-01), S. 148-153 |
Veröffentlichung: | Elsevier BV, 2015 |
Medientyp: | unknown |
ISSN: | 0021-9673 (print) |
DOI: | 10.1016/j.chroma.2015.03.037 |
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