Living Kidney Transplantation From Marginal Donors Presents Feasible Donor Renal Function Despite Inferior Recipient Renal Function
In: Transplantation Proceedings, Jg. 52 (2020-07-01), S. 1723-1728
Online
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Zugriff:
Kidney transplantation from marginal donors is an important solution for organ shortage problems. In this study, we evaluated the safety and effectiveness of living kidney transplantation from marginal donors at our hospitals.Between June 2006 and April 2019, 107 patients underwent living kidney transplantation at our hospitals. Marginal donors were defined as those with 1. age70 years, 2. hypertension, 3. creatinine clearance 80 mL/min, 4. body mass index30 kg/mThirty-one (29%) donors were defined as marginal. The primary reason for being defined as marginal was hypertension (74%). The mean age of the marginal donors (62 ± 10 years) was higher than that of standard donors (52 ± 12 years, P .001). The estimated glomerular filtration rate (eGFR) before and after transplantation was lower in the marginal group, whereas the decline ratio of eGFR was not different between the marginal and standard donors. Five-year graft survival of transplantations from marginal donors (89%) was not significantly inferior to that from standard donors (95%). Meanwhile, recipient eGFR was lower in transplantation from marginal donors than standard donors from 1 month through 5 years after transplantation.No significant differences were observed between the groups regarding the decline ratios of donor eGFR and graft survival. Thus, transplantation from marginal donors may be a feasible solution for donor shortage problems.
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Living Kidney Transplantation From Marginal Donors Presents Feasible Donor Renal Function Despite Inferior Recipient Renal Function
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Autor/in / Beteiligte Person: | Hamaya, Tomoko ; Togashi, Kyo ; Tomita, Hirofumi ; Yoneyama, Takahiro ; Fujita, Takeshi ; Hatakeyama, Shingo ; Narumi, Shunji ; Ohyama, Chikara ; Suzuki, Yuichiro ; Yoneyama, Tohru ; Hashimoto, Yasuhiro ; Hamano, Itsuto ; Murakami, Reiichi ; Yamamoto, Hayato |
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Zeitschrift: | Transplantation Proceedings, Jg. 52 (2020-07-01), S. 1723-1728 |
Veröffentlichung: | Elsevier BV, 2020 |
Medientyp: | unknown |
ISSN: | 0041-1345 (print) |
DOI: | 10.1016/j.transproceed.2020.01.157 |
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