Outcomes of chronic total occlusion percutaneous coronary intervention in patients with reduced left ventricular ejection fraction
In: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventionsREFERENCES, Jg. 99 (2022-01-06), Heft 4
Online
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Zugriff:
Background: The relationship between left ventricular ejection fraction (LVEF) and the success and safety of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. Methods: We examined the clinical characteristics and outcomes of CTO PCI in the Prospective Global Registry for the Study of CTO Intervention (PROGRESS-CTO) after stratifying patients by LVEF (≤35%, 36%–49%, and ≥50%). Results: A total of 7827 CTO PCI procedures with LVEF data were included. Mean age was 64 ± 10 years, 81% were men, 43% had diabetes mellitus, 61% had prior PCI, 45% had prior myocardial infarction, and 29% had prior coronary artery bypass graft surgery. Technical success was similar in the three LVEF strata: 85%, 86%, and 87%, p = 0.391 for LVEF ≤35%, 36%–49%, and ≥50%, respectively. In-hospital mortality was higher in lower LVEF patients (1.1%, 0.4%, and 0.3%, respectively, p = 0.001). In-hospital major adverse cardiovascular events (MACE) were numerically higher in lower EF patients (2.7%, 2.1%, and 1.9%, p = 0.271). At a median follow-up of 2 months (interquartile range: 19-350 days), patients with lower LVEF continued to have higher mortality (4.9%, 3.2%, and 1.4%, p < 0.001) while the MACE rates were similar (9.3%, 9.6%, and 7.4%, p = 0.172). Conclusion: CTO PCI can be performed with high technical success in patients with reduced LVEF but is associated with higher in-hospital and post-discharge mortality.
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Outcomes of chronic total occlusion percutaneous coronary intervention in patients with reduced left ventricular ejection fraction
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Autor/in / Beteiligte Person: | Simsek, Bahadir ; Kostantinis, Spyridon ; Karacsonyi, Judit ; Alaswad, Khaldoon ; Karmpaliotis, Dimitri ; Masoumi, Amirali ; Jaffer, Farouc A. ; Doshi, Darshan ; Khatri, Jaikirshan ; Poommipanit, Paul ; Gorgulu, Sevket ; Goktekin, Omer ; Krestyaninov, Oleg ; Davies, Rhian ; ElGuindy, Ahmed ; Jefferson, Brian K. ; Patel, Taral N. ; Patel, Mitul ; Chandwaney, Raj H. ; Mashayekhi, Kambis ; Galassi, Alfredo R. ; Rangan, Bavana V. ; Brilakis, Emmanouil S. ; Simsek, B. ; Kostantinis, S. ; Karacsonyi, J. ; Alaswad, K. ; Karmpaliotis, D. ; Masoumi, A. ; F.A., Jaffer ; Doshi, D. ; Khatri, J. ; Poommipanit, P. ; Gorgulu, S. ; Goktekin, O. ; Krestyaninov, O. ; Davies, R. ; ElGuindy, A. ; B.K., Jefferson ; T.N., Patel ; Patel, M. ; R.H., Chandwaney ; Mashayekhi, K. ; A.R., Galassi ; B.V., Rangan ; E.S., Brilakis |
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Zeitschrift: | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventionsREFERENCES, Jg. 99 (2022-01-06), Heft 4 |
Veröffentlichung: | 2022 |
Medientyp: | unknown |
ISSN: | 1522-726X (print) |
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