Response to pre-dilatation with POBA can predict target lesion revascularization after DCB angioplasty for de novo small coronary artery lesions
In: Journal of International Medical Research, Jg. 50 (2022-08-01), S. 030006052211137
Online
unknown
Zugriff:
Objective To assess the determinants of target lesion revascularization (TLR) after drug-coated balloon (DCB) angioplasty for de novo small coronary artery lesions. Methods This retrospective study enrolled consecutive lesions from patients that were in a stable condition and had undergone successful DCB treatment for de novo small coronary artery lesions. The study endpoint was TLR and major adverse cardiac events at 12 months. Results A total of 68 patients with 83 lesions were enrolled in the study. Of these, 11 (13.3%) lesions required TLR. Mean ± SD pre-dilatation balloon diameters were similar in the non-TLR (2.33 ± 0.72 mm) and TLR (2.18 ± 0.36 mm) groups. A comparison of the two groups showed that post/pre-lumen area ratio during pre-dilatation (%) by plain old balloon angioplasty (POBA) was significantly and negatively associated with TLR and the optimal cut-off point was 170%. Cox proportional hazard and multivariate regression analyses showed that post/pre-lumen area ratio was the only independent predictor of TLR (hazard ratio 0.9318; 95% confidence interval 0.9001, 0.9645). Conclusion Greater pre-dilatation using POBA, assessed as the post/pre-lumen area ratio, may be independently associated with a lower 12-month TLR rate in patients undergoing DCB angioplasty for de novo small coronary lesions.
Titel: |
Response to pre-dilatation with POBA can predict target lesion revascularization after DCB angioplasty for de novo small coronary artery lesions
|
---|---|
Autor/in / Beteiligte Person: | Takamura, Taka-aki ; Kawai, Yasuyuki ; Akita, Satori ; Oda, Minako ; Akao, Hironobu ; Nakagawa, Tohru ; Takama, Shunsuke ; Tsuchiya, Taketsugu ; Kitayama, Michihiko ; Kajinami, Kouji |
Link: | |
Zeitschrift: | Journal of International Medical Research, Jg. 50 (2022-08-01), S. 030006052211137 |
Veröffentlichung: | SAGE Publications, 2022 |
Medientyp: | unknown |
ISSN: | 1473-2300 (print) ; 0300-0605 (print) |
DOI: | 10.1177/03000605221113779 |
Schlagwort: |
|
Sonstiges: |
|