The Intestinal Gas Questionnaire (IGQ): Psychometric validation of a new instrument for measuring gas‐related symptoms and their impact on daily life among general population and irritable bowel syndrome
In: Neurogastroenterology & Motility, Jg. 34 (2021-06-18)
Online
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Zugriff:
Gas-related symptoms; Patient-reported outcomes; Quality of life Síntomas relacionados con los gases; Resultados informados por el paciente; Calidad de vida Símptomes relacionats amb els gasos; Resultats informats pel pacient; Qualitat de vida Background Gas-related symptoms (GRS) are common in the general population (GPop) and among patients with disorders of gut-brain interactions but there is no patient-reported outcome evaluating these symptoms and their impact on daily life. We have previously developed a 43-item intestinal gas questionnaire (IGQ). The aim of the present study is to perform a psychometric validation of this instrument. Methods Participants (119 from the GPop and 186 irritable bowel syndrome (IBS) patients) were recruited from 3 countries (UK, Spain, France). IBS patients fulfilled ROME IV criteria with an IBS severity score between 150 and 300. Participants completed the IGQ, the functional Digestive Disorders Quality of Life (FDDQL), and the EQ-5D. A subgroup (n = 90) repeated the IGQ completion after 7 days on paper or electronically. Results From the original IGQ questionnaire, 26 items were deleted because of poor performance. Confirmatory factorial analysis on the remaining 17 items (7 symptom and 10 impact items) yielded a 6-factor structure accounting for 67% of the variance for bloating (6 items), flatulence (3), belching (2), bad breath (2), stomach rumbling (2), and difficult gas evacuation (2). Global score (0-100) was worse among IBS vs GPop (40 ± 15 vs 33 ± 17; p = 0.0016). At the second visit, the intraclass correlation coefficient of IGQ scores was between 0.71 and 0.86 (n = 67) for test-retest reliability and 0.61-0.87 (n = 64) for equivalence between electronic and paper versions of IGQ. Conclusion The IGQ available in paper and electronic versions in 3 languages is a robust instrument for capturing and measuring GRS and their impact on daily life. This Investigator Sponsored Study has been funded by Danone Research. Danone did not interfere with the analysis and interpretation of data. The work was supported in part by the Spanish Ministry of Economy and Competitiveness (Dirección General de Investigación Científica y Técnica, SAF 2016-76648-R). Ciberehd is funded by the Instituto de Salud Carlos III
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The Intestinal Gas Questionnaire (IGQ): Psychometric validation of a new instrument for measuring gas‐related symptoms and their impact on daily life among general population and irritable bowel syndrome
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Autor/in / Beteiligte Person: | Guagnozzi, Danila ; Thonon, Frederique ; Coffin, Benoit ; Lobo, Beatriz ; Duracinsky, Martin ; Whorwell, Peter J. ; Bessonneau, Pascal ; Chassany, Olivier ; Azpiroz, Fernando ; Santos, Javier ; Payakachat, Nalin ; Archbold, Sharon ; Institut Català de la Salut ; [Duracinsky M] Patient-Centered Reported Outcomes, Paris-Diderot University, Paris, France. Health Economics Clinical Trial Unit (URC-ECO), Hotel-Dieu Hospital, AP-HP, Paris, France. [Archbold S] Neurogastroenterology Unit, School of Medical Sciences, Faculty of Biology, Medicine and Health, Wythenshawe Hospital, University of Manchester, Manchester, UK. [Lobo B, Santos J, Guagnozzi D, Azpiroz F] Unitat de Recerca en Aparell Digestiu, Unitat de Fisiologia i Fisiopatologia Digestiva, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de l’Aparell Digestiu, Vall d’Hebron Hospital Universitari, Barcelona, Spain. CIBER de Enfermedades Hepaticas y Digestivas (CIBERHED), Instituto de Salud Carlos III, Madrid, Spain. Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Bessonneau P, Thonon F] Patient-Centered Reported Outcomes, Paris-Diderot University, Paris, France ; Vall d'Hebron Barcelona Hospital Campus |
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Zeitschrift: | Neurogastroenterology & Motility, Jg. 34 (2021-06-18) |
Veröffentlichung: | Wiley, 2021 |
Medientyp: | unknown |
ISSN: | 1365-2982 (print) ; 1350-1925 (print) |
DOI: | 10.1111/nmo.14202 |
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