The future of therapy for alcoholic hepatitis – Beyond corticosteroids
In: Journal of Hepatology, Jg. 70 (2019), Heft 4, S. 785-787
Online
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Zugriff:
Corticosteroids are the only treatment proven to reduce mortality from severe alcoholic hepatitis (SAH), though the benefit is short-lived.1 Several potential therapies are currently under evaluation in human clinical trials (Table 1). These therapies target: i) malnutrition; ii) intestinal dysbiosis and its portal translocation; iii) bile acid production; iv) hepatocyte death; v) hepatocyte regeneration; and vi) life-threatening complications of the disease itself.
Titel: |
The future of therapy for alcoholic hepatitis – Beyond corticosteroids
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Autor/in / Beteiligte Person: | Vergis, N ; Atkinson, S ; Thursz, M ; Medical Research Council (MRC) ; Wellcome Trust, ISSF |
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Zeitschrift: | Journal of Hepatology, Jg. 70 (2019), Heft 4, S. 785-787 |
Veröffentlichung: | Elsevier, 2019 |
Medientyp: | unknown |
ISSN: | 1600-0641 (print) ; 0168-8278 (print) |
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