DeconMSn: a software tool for accurate parent ion monoisotopic mass determination for tandem mass spectra
Oxford University Press, 2008
academicJournal
Zugriff:
Summary: DeconMSn accurately determines the monoisotopic mass and charge state of parent ions from high-resolution tandem mass spectrometry data, offering significant improvement for LTQ_FT and LTQ_Orbitrap instruments over the commercially delivered Thermo Fisher Scientific's extract_msn tool. Optimal parent ion mass tolerance values can be determined using accurate mass information, thus improving peptide identifications for high-mass measurement accuracy experiments. For low-resolution data from LCQ and LTQ instruments, DeconMSn incorporates a support-vector-machine-based charge detection algorithm that identifies the most likely charge of a parent species through peak characteristics of its fragmentation pattern. Availability: http://ncrr.pnl.gov/software/ or http://www.proteomicsresource.org/ Contact: rds@pnl.gov Supplementary information: PowerPoint presentation/Poster on http://ncrr.pnl.gov/software/ .
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DeconMSn: a software tool for accurate parent ion monoisotopic mass determination for tandem mass spectra
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Autor/in / Beteiligte Person: | Mayampurath, Anoop M. ; Jaitly, Navdeep ; Purvine, Samuel O. ; Monroe, Matthew E. ; Auberry, Kenneth J. ; Adkins, Joshua N. ; Smith, Richard D. |
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Veröffentlichung: | Oxford University Press, 2008 |
Medientyp: | academicJournal |
DOI: | 10.1093/bioinformatics/btn063 |
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