Integrative chemoproteomics reveals anticancer mechanisms of silver(i) targeting the proteasome regulatory complex
In: Chemical Science, Jg. 15 (2024), Heft 14, S. 5349-5359
Online
academicJournal
Zugriff:
A silver( i ) complex AgTU exerts anticancer activities by releasing Ag + ions that target and impair the 19S proteasomal complex, resulting in accumulation of ubiquitinated, misfolded proteins.
Titel: |
Integrative chemoproteomics reveals anticancer mechanisms of silver(i) targeting the proteasome regulatory complex
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Autor/in / Beteiligte Person: | Shao, Xiaojian ; Xing, Fangrong ; Zhang, Yiwei ; Lok, Chun-Nam ; Che, Chi-Ming ; Innovation and Technology Commission - Hong Kong |
Link: | |
Zeitschrift: | Chemical Science, Jg. 15 (2024), Heft 14, S. 5349-5359 |
Veröffentlichung: | Royal Society of Chemistry (RSC), 2024 |
Medientyp: | academicJournal |
ISSN: | 2041-6520 |
DOI: | 10.1039/d3sc04834a |
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