Inhibition of Notch activity by the gamma-secretase inhibitor DBZ abolished the upregulation of SNAI1 induced by EGF and VEGF.
2022
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Zugriff:
PANC-1 cells were treated with 20 ng/ml of either EGF or VEGF or 1 nM DBZ and cultured for 48 hours. The expression of SNAI1 was determined by quantitative RT-PCR. Data presented ± S.D. * P Value < 0.01 (n = 3). (TIF)
Titel: |
Inhibition of Notch activity by the gamma-secretase inhibitor DBZ abolished the upregulation of SNAI1 induced by EGF and VEGF.
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Autor/in / Beteiligte Person: | Nontawat Benjakul (14295081) ; Nattapa Prakobphol (14295084) ; Chayada Tangshewinsirikul (4678393) ; Wirada Dulyaphat (14295087) ; Jisnuson Svasti (2427940) ; Komgrid Charngkaew (4385962) ; Thaned Kangsamaksin (4678396) |
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Veröffentlichung: | 2022 |
Medientyp: | Bild |
DOI: | 10.1371/journal.pone.0279001.s004 |
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