The Role of Socioeconomic Status in the Association of Lung Function and Air Pollution—A Pooled Analysis of Three Adult ESCAPE Cohorts
In: ISSN: 1661-7827, 2019
Online
academicJournal
Zugriff:
International audience ; Ambient air pollution is a leading environmental risk factor and its broad spectrum of adverse health effects includes a decrease in lung function. Socioeconomic status (SES) is known to be associated with both air pollution exposure and respiratory function. This study assesses the role of SES either as confounder or effect modifier of the association between ambient air pollution and lung function. Cross-sectional data from three European multicenter adult cohorts were pooled to assess factors associated with lung function, including annual means of home outdoor NO2. Pre-bronchodilator lung function was measured according to the ATS-criteria. Multiple mixed linear models with random intercepts for study areas were used. Three different factors (education, occupation and neighborhood unemployment rate) were considered to represent SES. NO2 exposure was negatively associated with lung function. Occupation and neighborhood unemployment rates were not associated with lung function. However, the inclusion of the SES-variable education improved the models and the air pollution-lung function associations got slightly stronger. NO2 associations with lung function were not substantially modified by SES-variables. In this multicenter European study we could show that SES plays a role as a confounder in the association of ambient NO2 exposure with lung function.
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The Role of Socioeconomic Status in the Association of Lung Function and Air Pollution—A Pooled Analysis of Three Adult ESCAPE Cohorts
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Autor/in / Beteiligte Person: | Keidel, Dirk ; Anto, Josep Maria ; Basagaña, Xavier ; Bono, Roberto ; Burte, Emilie ; Carsin, Anne-Elie ; Forsberg, Bertil ; Fuertes, Elaine ; Galobardes, Bruna ; Heinrich, Joachim ; de Hoogh, Kees ; Jarvis, Debbie ; Künzli, Nino ; Leynaert, Bénédicte ; Marcon, Alessandro ; Le Moual, Nicole ; de Nazelle, Audrey ; Schindler, Christian ; Siroux, Valérie ; Stempfelet, Morgane ; Sunyer, Jordi ; Temam, Sofia ; Tsai, Ming-Yi ; Varraso, Raphaëlle ; Jacquemin, Bénédicte ; Probst-Hensch, Nicole ; Swiss Tropical and Public Health Institute Basel ; Université de Bâle = University of Basel = Basel Universität (Unibas) ; Instituto de Salud Global - Institute For Global Health Barcelona (ISGlobal) ; Hospital del Mar Medical Research Institute Barcelone, Espagne (IMIM) ; Universitat Pompeu Fabra Barcelona (UPF) ; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health (CIBERESP) ; Università degli studi di Torino = University of Turin (UNITO) ; Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA) ; Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM) ; Umeå University, Sweden ; Imperial College London ; University of Bristol Bristol ; Helmholtz Zentrum München = German Research Center for Environmental Health ; Ludwig Maximilian University Munich = Ludwig Maximilians Universität München (LMU) ; Physiopathologie et Epidémiologie des Maladies Respiratoires (PHERE (UMR_S_1152 / U1152)) ; Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM) ; Università degli studi di Verona = University of Verona (UNIVR) ; Université Grenoble Alpes (UGA) ; Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB) ; Centre Hospitalier Universitaire CHU Grenoble (CHUGA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes 2016-2019 (UGA 2016-2019 ) ; Département santé travail (DST-InVS) ; Institut de Veille Sanitaire (INVS) ; University of Washington Seattle |
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Zeitschrift: | ISSN: 1661-7827, 2019 |
Veröffentlichung: | HAL CCSD ; MDPI, 2019 |
Medientyp: | academicJournal |
DOI: | 10.3390/ijerph16111901 |
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