Management of Patients with Pancreatic Ductal Adenocarcinoma in the Real-Life Setting: Lessons from the French National Hospital Database
In: Cancers, Vol 13, Iss 3515, p 3515 (2021, Jg. 13 (2021), Heft 3515, p 3515
Online
academicJournal
Zugriff:
Pancreatic ductal adenocarcinoma (PDAC) remains a major public health challenge, and faces disparities and delays in the diagnosis and access to care. Our purposes were to describe the medical path of PDAC patients in the real-life setting and evaluate the overall survival at 1 year. We used the national hospital discharge summaries database system to analyze the management of patients with newly diagnosed PDAC over the year 2016 in Auvergne-Rhône-Alpes region (AuRA) (France). A total of 1872 patients met inclusion criteria corresponding to an incidence of 22.6 per 100,000 person-year. Within the follow-up period, 353 (18.9%) were operated with a curative intent, 743 (39.7%) underwent chemo- and/or radiotherapy, and 776 (41.4%) did not receive any of these treatments. Less than half of patients were operated in a high-volume center, defined by more than 20 PDAC resections performed annually, mainly university hospitals. The 1-year survival rate was 47% in the overall population. This study highlights that a significant number of patients with PDAC are still operated in low-volume centers or do not receive any specific oncological treatment. A detailed analysis of the medical pathways is necessary in order to identify the medical and territorial determinants and their impact on the patient’s outcome.
Titel: |
Management of Patients with Pancreatic Ductal Adenocarcinoma in the Real-Life Setting: Lessons from the French National Hospital Database
|
---|---|
Autor/in / Beteiligte Person: | Christelle de la Fouchardière ; Adham, Mustapha ; Marion-Audibert, Anne-Marie ; Duclos, Antoine ; Darcha, Claude ; Berthelet, Olivier ; Hervieu, Valérie ; Artru, Pascal ; Labrosse, Hélène ; Fayet, Yohan ; Ferroud-Plattet, Bruno ; Aublet-Cuvellier, Bruno ; Chambon, Georges ; Baconnier, Mathieu ; Rebischung, Christine ; Farsi, Fadila ; Ray-Coquard, Isabelle ; Mastier, Charles ; Ternamian, Pierre-Jean ; Williet, Nicolas ; Buc, Emmanuel ; Walter, Thomas ; Herr, Andrée-Laure |
Link: | |
Zeitschrift: | Cancers, Vol 13, Iss 3515, p 3515 (2021, Jg. 13 (2021), Heft 3515, p 3515 |
Veröffentlichung: | MDPI AG, 2021 |
Medientyp: | academicJournal |
ISSN: | 2072-6694 (print) |
DOI: | 10.3390/cancers13143515 |
Schlagwort: |
|
Sonstiges: |
|