Activating and inactivating mutations of the human, rat, equine and eel luteinizing hormone/ chorionic gonadotropin receptors (LH/CGRs)
In: Journal of Animal Reproduction and Biotechnology, Jg. 36 (2021), Heft 4, S. 167-174
academicJournal
Zugriff:
Mutations in the luteinizing hormone/chorionic gonadotropin receptors (LH/CGRs), representatives of the G protein-coupled receptor family, have been rapidly identified over the last 20 years. This review aims to compare and analyze the data reported the activating and inactivating mutations of the LH/CGRs between human, rat, equine and fish, specifically (Japanese eel Anguilla japonica). Insights obtained through detailed study of these naturally-occurring mutations provide a further update of structure-function relationship of these receptors. Specifically, we present a variety of data on eel LH/CGR. These results provide important information about LH/CGR function in fish and the regulation of mutations of the highly conserved amino acids in glycoprotein hormone receptors.
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Activating and inactivating mutations of the human, rat, equine and eel luteinizing hormone/ chorionic gonadotropin receptors (LH/CGRs)
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Autor/in / Beteiligte Person: | Min, Kwan-Sik ; Byambaragchaa, Munkhzaya ; Choi, Seung-Hee ; Joo, Hyo-Eun ; Kim, Sang-Gwon ; Kim, Yean-Ji ; Park, Gyeong-Eun |
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Zeitschrift: | Journal of Animal Reproduction and Biotechnology, Jg. 36 (2021), Heft 4, S. 167-174 |
Veröffentlichung: | The Korean Society of Animal Reproduction and Biotechnology, 2021 |
Medientyp: | academicJournal |
ISSN: | 2671-4639 (print) ; 2671-4663 (print) |
DOI: | 10.12750/JARB.36.4.169 |
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