Comparison between dynamic versus static models and real-time monitoring of neuronal dysfunction in an amyloid-β induced neuronal toxic model on a chip platform
In: Lab on a Chip, Jg. 24 (2024), Heft 7, S. 1887-1902
Online
academicJournal
Zugriff:
A 3D neural spheroid-based system with an interstitial level of flow for simulating the brain microenvironment toward a dynamic amyloid-β induced neuronal toxic model was established. A real-time impedance recording was used to monitor the neural network formation and disconnection.
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Comparison between dynamic versus static models and real-time monitoring of neuronal dysfunction in an amyloid-β induced neuronal toxic model on a chip platform
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Autor/in / Beteiligte Person: | Liang, Chu-Chun ; Chen, Po-Yen ; Liu, Nien-Che ; Lee, I-Chi ; Ministry of Science and Technology, Taiwan ; National Tsing Hua University ; Chang Gung University ; University of Maryland |
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Zeitschrift: | Lab on a Chip, Jg. 24 (2024), Heft 7, S. 1887-1902 |
Veröffentlichung: | Royal Society of Chemistry (RSC), 2024 |
Medientyp: | academicJournal |
ISSN: | 1473-0197 |
DOI: | 10.1039/d3lc00507k |
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