Induction of Plasmodium-specific immune responses using liposome-based vaccines
Frontiers Research Foundation, 2019
Online
academicJournal
Zugriff:
In the development of vaccines, the ability to initiate both innate and subsequent adaptive immune responses need to be considered. Live attenuated vaccines achieve this naturally, while inactivated and sub-unit vaccines generally require additional help provided through delivery systems and/or adjuvants. Liposomes present an attractive adjuvant/delivery system for antigens. Here, we review the key aspects of immunity against Plasmodium parasites, liposome design considerations and their current application in the development of a malaria vaccine.
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Induction of Plasmodium-specific immune responses using liposome-based vaccines
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Autor/in / Beteiligte Person: | Ssemaganda, Aloysious ; Giddam, Ashwini Kumar ; Zaman, Mehfuz ; Skwarczynski, Mariusz ; Toth, Istvan ; Stanisic, Danielle I. ; Good, Michael F. |
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Veröffentlichung: | Frontiers Research Foundation, 2019 |
Medientyp: | academicJournal |
ISSN: | 1664-3224 (print) |
DOI: | 10.3389/fimmu.2019.00135 |
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