Kidney function and renal resistive index in children with juvenile idiopathic arthritis. ...
Springer Science and Business Media LLC, 2023
academicJournal
Zugriff:
Juvenile idiopathic arthritis (JIA) is a common pediatric rheumatic disease. Renal manifestations have been rarely observed in JIA, although amyloidosis could be a renal complication in systemic JIA (sJIA). To investigate renal damage in JIA children and to establish the relationship with treatment. Blood urea nitrogen (BUN), creatinine, cystatin C (CysC), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), urinary albumin excretion (UAE), estimated glomerular filtration rate (eGFR), and renal resistive index (RRI) were assessed in 49 JIA children (9 boys/40 girls, mean age 10.3 ± 3.8 years) and in 49 healthy controls (24 boys/25 girls, mean age 11.3 ± 3.4 years). Twenty-two JIA patients were on methotrexate (MTX) therapy (group A) and 27 on biologic drugs (group B). CysC and BUN (respectively, 0.8 ± 0.1 vs. 0.7 ± 0.1 mg/dl; 13.3 ± 2.9 vs. 11.7 ± 1.4 mg/dl) were higher (p ≤ 0.001) whereas creatinine and eGFR (respectively, 0.5 ± 0.1 vs. 0.6 ± 0.1 mg/dl; 99.2 ± 10.5 vs. 122.5 ± 19.8 ml/min/1.73 ...
Titel: |
Kidney function and renal resistive index in children with juvenile idiopathic arthritis. ...
|
---|---|
Autor/in / Beteiligte Person: | Cafarotti, Alessandro ; Marcovecchio, Maria Loredana ; Lapergola, Giuseppe ; Di Battista, Caterina ; Marsili, Manuela ; Basilico, Raffaella ; Di Donato, Giulia ; David, Daniela ; Pelliccia, Piernicola ; Chiarelli, Francesco ; Breda, Luciana |
Link: | |
Veröffentlichung: | Springer Science and Business Media LLC, 2023 |
Medientyp: | academicJournal |
DOI: | 10.17863/cam.88707 |
Schlagwort: |
|
Sonstiges: |
|