Long-term outcomes of a randomized controlled trial comparing trans-obturator vaginal mesh with native tissue repair in the treatment of anterior vaginal wall prolapse
In: ISSN: 0937-3462, 2020
academicJournal
Zugriff:
International audience ; Introduction and hypothesis: The aim of this study was to report the long-term subjective and objective outcomes after transvaginal mesh (TVM) or native tissue repair.Methods: Prospective, randomized, multicenter study conducted between April 2005 and December 2009 comparing anterior colporrhaphy with trans-obturator vaginal mesh (Pelvitex/Ugytex®, Sofradim, Trevoux, France) for the treatment of anterior vaginal wall prolapse. The primary endpoint was functional recurrence rate 5-8 years after surgery. Secondary endpoints consisted of anatomical results, mesh-related morbidity and patient satisfaction measured through validated questionnaires.Results: Of the 147 women originally included, 75 (51%) were successfully re-contacted a median of 7 years after the initial surgery. The primary outcome, subjective recurrence of prolapse, was similar between the TVM and the anterior colporrhaphy groups (31 vs 34% respectively). Anatomical recurrence was less likely in the TVM group (67 vs 24%, p = 0.004). Mesh exposure occurred in 4 of the 39 patients (13%) during follow-up, 2 of which had a surgical reintervention. Reintervention for prolapse took place in 7 patients (9%).Conclusion: Seven-year follow-up showed similar functional outcomes for mesh and native tissue repair in anterior vaginal wall prolapse. TVM did not reduce repeat surgery in the long term; it did, however, reduce anatomical recurrence. Mesh exposure rates were relatively high, but no difference in outcome of pain or dyspareunia was noted.
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Long-term outcomes of a randomized controlled trial comparing trans-obturator vaginal mesh with native tissue repair in the treatment of anterior vaginal wall prolapse
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Autor/in / Beteiligte Person: | Allegre, Lucie ; Callewaert, Geertje ; Alonso, Sandrine ; Cornille, Arnaud ; Fernandez, Hervé ; Eglin, Georges ; De Tayrac, Renaud ; Centre Hospitalier Universitaire de Nîmes (CHU Nîmes) ; Université de Montpellier (UM) ; University Hospitals Leuven Leuven ; BESPIM ; Clinique Beau Soleil Montpellier ; Bicêtre, Hôpital ; Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bicêtre |
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Zeitschrift: | ISSN: 0937-3462, 2020 |
Veröffentlichung: | HAL CCSD ; Springer Verlag, 2020 |
Medientyp: | academicJournal |
DOI: | 10.1007/s00192-019-04073-x |
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