Construction of Hydrodibenzo[ b , d ]furan Frameworks from Morita–Baylis–Hillman Carbonates of Isatins and o ‑Hydroxy Enones via Palladium and Brønsted Base Relay Catalysis
2021
academicJournal
Zugriff:
A cascade assembly between isatin-derived Morita–Baylis–Hillman carbonates and o -hydroxybenzylideneacetones has been developed under the relay catalysis of Pd(PPh 3 ) 4 and DBU, affording a spectrum of 1,2,3,4-tetrahydrodibenzo[ b , d ]furan architectures incorporating a spirooxindole motif in moderate to good yields with excellent diastereoselectivity. The fused indole analogues were similarly furnished by employing the benzylideneacetones having an o -TsNH group.
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Construction of Hydrodibenzo[ b , d ]furan Frameworks from Morita–Baylis–Hillman Carbonates of Isatins and o ‑Hydroxy Enones via Palladium and Brønsted Base Relay Catalysis
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Autor/in / Beteiligte Person: | Ze-Liang He (11823756) ; Peng Chen (6514) ; Zhi-Chao Chen (5793035) ; Wei Du (88790) ; Ying-Chun Chen (712090) |
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Veröffentlichung: | 2021 |
Medientyp: | academicJournal |
DOI: | 10.1021/acs.orglett.1c03689.s001 |
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