Bariatric surgery and liver transplantation, here we are now: A French nationwide retrospective study
In: ISSN: 2210-7401, 2023
Online
academicJournal
Zugriff:
International audience ; At the time of the growing obesity epidemic worldwide, liver transplantation (LT) and metabolic syndrome are closely linked: non-alcohol-related fatty liver disease (NAFLD) is one of the leading indications for liver transplantation, and metabolic syndrome can also appear after liver transplantation, in relation to immunosuppressive medications and weight gain, whatever was the initial liver disease leading to the indication of LT. Therefore, the role of bariatric surgery (BS) is important due to its longer-lasting effect and efficacy. We performed a retrospective review of all 50 adult French liver transplant recipients who had a history of bariatric surgery, including 37 procedures before transplantation, and 14 after. There were three significantly different characteristics when comparing pre-and post-LT BS: patients were older (at the time of BS), presented more frequently arterial hypertension (at the time of LT), and the proportion of NAFLD as initial liver disease leading to LT was lower, in the post-LT group. Regarding pre-LT BS, in one case BS was complicated by liver failure leading to the rapid indication of LT; it was the single patient for whom the delay between BS and LT was less than 1 year; there was no patient who specifically underwent BS for the purpose of LT listing.
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Bariatric surgery and liver transplantation, here we are now: A French nationwide retrospective study
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Autor/in / Beteiligte Person: | Dumortier, Jérôme ; Erard, Domitille ; Villeret, François ; Faitot, François ; Duvoux, Christophe ; Faure, Stéphanie ; Francoz, Claire ; Gugenheim, Jean ; Hardwigsen, Jean ; Hiriart, Jean-Baptiste ; Houssel-Debry, Pauline ; Bello, Arnaud Del ; Lassailly, Guillaume ; Vanlemmens, Claire ; Saliba, Faouzi ; Altman, Clara ; Latournerie, Marianne ; Dharancy, Sébastien ; Debs, Tarek ; Hospices Civils de Lyon (HCL) ; Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon ; Hôpital Henri Mondor ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12) ; Département d'Hépato-Gastroentérologie et de Transplantation Hépatique CHU Saint-Eloi ; Hôpital Saint Eloi (CHRU Montpellier) ; Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Université de Montpellier (UM) ; Service d’Hépatologie Hôpital Beaujon ; Hôpital Beaujon AP-HP ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP) ; Hôpital Archet 2 Nice (CHU) ; Hôpital Haut-Lévêque CHU Bordeaux ; Bordeaux, CHU ; Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Ponchaillou ; Institut de recherche en santé, environnement et travail (Irset) ; Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique EHESP (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) ; Hôpital Claude Huriez Lille ; Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille) ; Centre hépato-biliaire (CHB) ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM) ; Bourse d'appels offres à recherche 2018 – Agence de la Biomédecine. |
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Zeitschrift: | ISSN: 2210-7401, 2023 |
Veröffentlichung: | HAL CCSD ; Elsevier, 2023 |
Medientyp: | academicJournal |
DOI: | 10.1016/j.clinre.2023.102164 |
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