Potencijal monoterpena karvakrola i geraniola u inhibiciji oralnih patogena ; Antibacterial potential of the monoterpenes carvacrol and geraniol against oral pathogens

Cilj istraživanja bio je ispitivanje antimikrobnog potencijala monoterpena karvakrola i geraniola na bakterijskim izolatima Streptococcus spp. od značaja za etiologiju karijesa (S. mutans, S. sanguinis, S. parasanguinis, S. gordonii). Antimikrobni potencijal karvakrola i geraniola testiran je mikrodilucionim testom, kojim su određene minimalna inhibitorna koncentracija (MIC) i minimalna baktericidna koncentracija (MBC). Testirani monoterpeni ispoljili su značajan antimikrobni potencijal, MIC je bio u opsegu od 0.55 mg/mL do 4.39 mg/mL, a MBC od 2.20 mg/mL do 19.54 mg/mL. ; The aim of our study was to investigate the antimicrobial potential of monoterpenes carvacrol and geraniol towards the Streptococcus spp. isolates relevant to tooth caries (S. mutans, S. sanguinis, S. parasanguinis, S gordonii). Microdilution test was used for the assessment of the antimicrobial potential of carvacrol and geraniol, and the minimal inhibitory concentrations (MICs) and minimal bactericidal concentrations (MBCs) were determined. Tested monoterpenes achieved notable antimicrobial activity, with MICs ranging from 0.55 mg/mL to 4.39 mg/mL, and MBCs from 2.20 mg/mL to 19.54 mg/mL. ; 59th Meeting of the Serbian Chemical Society; June 1-2, 2023, Novi Sad, Serbia