Oxidative C-C Coupling Reactions of Benzofused Heterocycles Utilizing DDQ
In: Villafane, Louis (2014) Oxidative C-C Coupling Reactions of Benzofused Heterocycles Utilizing DDQ. Master's Thesis, University of Pittsburgh. (Unpublished); (2014)
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Hochschulschrift
Zugriff:
2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) mediated oxidative coupling chemistry that was previously developed in the Floreancig group for coupling with chromene cations has been expanded to include other benzofused heterocycles, including benzoxathioles, and is described herin. The reactivity of these cationic intermediates was utilized to rapidly furnish coupled benzofused heterocycles. The reactivity of the cationic intermediates was explored via addition of a number of nucleophiles and the electronics of the substrate were altered to determine the scope of the substrate in this type of transformation. In addition a one-pot method was developed to access spiro compounds, in the orthoester oxidation state, containing a synthetic handle for further manipulation.
Titel: |
Oxidative C-C Coupling Reactions of Benzofused Heterocycles Utilizing DDQ
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Autor/in / Beteiligte Person: | Villafane, Louis |
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Quelle: | Villafane, Louis (2014) Oxidative C-C Coupling Reactions of Benzofused Heterocycles Utilizing DDQ. Master's Thesis, University of Pittsburgh. (Unpublished); (2014) |
Veröffentlichung: | 2014 |
Medientyp: | Hochschulschrift |
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