Phase shifting two coupled circadian pacemakers - Implications for jet lag
In: Other Sources, 1985
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Zugriff:
Two Van der Pol oscillators with reciprocal linear velocity coupling are utilized to model the response of the human circadian timing system to abrupt displacements of the environmental time cues (zeitgebers). The core temperature rhythm and sleep-wake cycle simulated by the model are examined. The relationship between the masking of circadian rhythms by environmental variables and behavioral and physiological events and the rates of resynchronization is studied. The effects of zeitgeber phase shifts and zeitgeber strength on the resynchronization rates are analyzed. The influence of intrinsic pacemakers periods and coupling strength on resynchronization are investigated. The simulated data reveal that: resynchronization after a time zone shift depends on the magnitude of the shift; the time of day of the shift has little influence on resynchronization; the strength of zeitgebers affects the rate and direction of the resynchronization; the intrinsic pacemaker periods have a significant effect on resynchronization; and increasing the coupling between the oscillators results in an increase in the rate of resynchronization. The model data are compared to transmeridian flight studies data and similar resynchronization patterns are observed.
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Phase shifting two coupled circadian pacemakers - Implications for jet lag
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Autor/in / Beteiligte Person: | Gander, P. H. ; Kronauer, R. E. ; Graeber, R. C. |
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Zeitschrift: | Other Sources, 1985 |
Veröffentlichung: | 1985 |
Medientyp: | unknown |
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