Solvent‐free Hydrogenation of Squalene using Parts per Million Levels of Palladium Supported on Carbon Nanotubes: Shift from Batch Reactor to Continuous‐Flow System
In: ISSN: 1864-5631, 2022
Online
academicJournal
Zugriff:
International audience ; The transition from batch catalytic processes to continuous flow processes requires highly active and stable catalysts that still need to be developed. The preparation and characterization of catalysts where palladium single atoms and nanoparticles are simultaneously present on carbon nanotubes were recently reported by us. These catalysts are considerably more active than commercial or previously described catalysts for the liquid phase hydrogenation of terpenes. Herein is shown that under solvent-free conditions, squalene (SQE) could be converted into squalane (SQA,>98 %) using only 300 ppm of Pd in less than 1.4 h at 20 bar H2 and 120 °C. Catalyst stability was assessed in a lab-scale flow reactor, and long-term experiments led to turnover number (TON) higher than 300000 without any detectable loss in the activity. Then, the implementation of this catalyst in a commercial intensified continuous-flow milli-reactor pilot was achieved. High purity SQA (>98 %) could be obtained by continuous hydrogenation of solvent-free SQE at 180 °C and 30 bar H2 with a contact time below 15 min. A production capacity of 3.6 kg per day of SQA could be obtained with an effective reactor volume (VR) of 43.2 mL for this complex 3 phase reaction. Large-scale production can now be foreseen thanks to seamless scale-up provided by the continuous flow pilot supplier.
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Solvent‐free Hydrogenation of Squalene using Parts per Million Levels of Palladium Supported on Carbon Nanotubes: Shift from Batch Reactor to Continuous‐Flow System
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Autor/in / Beteiligte Person: | Guicheret, Boris ; Vanoye, Laurent ; Rivera-Cárcamo, Camila ; de Bellefon, Claude ; Serp, P. ; Philippe, Régis ; Favre-Réguillon, Alain ; Catalyse, Polymérisation, Procédés et Matériaux (CP2M) ; Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon-Université de Lyon-École Supérieure de Chimie Physique Électronique de Lyon (CPE)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS) ; Laboratoire de chimie de coordination (LCC) ; Institut de Chimie de Toulouse (ICT) ; Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS) ; Conservatoire National des Arts et Métiers CNAM (CNAM) ; HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM) ; Region Auvergne-Rhône-Alpes (contract number 15 021131 01 – CNR006) through the 20th FUI call ; ANR-19-CE07-0030,COMET,Catalyse Coopérative Entre Atomes Et Nanoparticules Métalliques(2019) |
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Zeitschrift: | ISSN: 1864-5631, 2022 |
Veröffentlichung: | HAL CCSD ; ChemPubSoc Europe/Wiley, 2022 |
Medientyp: | academicJournal |
DOI: | 10.1002/cssc.202200916 |
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