WAO consensus on definition of food allergy severity (DEFASE)
In: THE WORLD ALLERGY ORGANIZATION JOURNAL, 2023, Heft 3, S. 100753
Online
academicJournal
Zugriff:
Background: While several scoring systems for the severity of anaphylactic reactions have been developed, there is a lack of consensus on definition and categorisation of severity of food allergy disease as a whole. Aim: To develop an international consensus on the severity of food allergy (DEfinition of Food Allergy Severity, DEFASE) scoring system, to be used globally. Methods phase 1: We conducted a mixed-method systematic review (SR) of 11 databases for published and unpublished literature on severity of food allergy management and set up a panel of international experts. Phase 2: Based on our findings in Phase 1, we drafted statements for a two-round modified electronic Delphi (e-Delphi) survey. A purposefully selected multidisciplinary international expert panel on food allergy (n=60) was identified and sent a structured questionnaire, including a set of statements on different domains of food allergy severity related to symptoms, health-related quality of life, and economic impact. Participants were asked to score their agreement on each statement on a 5-point Likert scale ranging from "strongly agree" to "strongly disagree". Median scores and percentage agreements were calculated. Consensus was defined a priori as being achieved if 70% or more of panel members rated a statement as "strongly agree" to "agree" after the second round. Based on feedback, 2 additional online voting rounds were conducted. Results: We received responses from 92% of Delphi panel members in round 1 and 85% in round 2. Consensus was achieved on the overall score and in all of the 5 specific key domains as essential components of the DEFASE score. Conclusions: The DEFASE score is the first comprehensive grading of food allergy severity that considers not only the severity of a single reaction, but the whole disease spectrum. An international consensus has been achieved regarding a scoring system for food allergy disease. It offers an evaluation grid, which may help to rate the severity of food allergy. Phase 3 will involve ...
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WAO consensus on definition of food allergy severity (DEFASE)
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Autor/in / Beteiligte Person: | Arasi, S. ; Nurmatov, U. ; Dunn-Galvin, A. ; Roberts, G. ; Turner, P. J. ; Shinder, S. B. ; Gupta, R. ; Eigenmann, P. ; Nowak-Wegrzyn, A. ; Ansotegui, I. J. ; Rivas, M. F. ; Petrou, S. ; Tanno, L. K. ; Vazquez-Ortiz, M. ; Vickery, B. ; Wong, G. ; Alvaro-Lozano, M. ; Asaria, M. ; Begin, P. ; Bozzola, M. ; Boyle, R. ; Brough, H. ; Cardona, V. ; Chinthrajah, R. S. ; Cianferoni, A. ; Deschildre, A. ; Fleischer, D. ; Gazzani, F. ; Gerdts, J. ; Giannetti, M. ; Greenhawt, M. ; Guzman, M. A. ; Hossny, E. ; Kauppi, P. ; Jones, C. ; Lucidi, F. ; Monge Ortega O. P. ; Munblit, D. ; Muraro, A. ; Pajno, G. ; Podesta, M. ; Rodriguez del Rio P. ; Said, M. ; Santos, A. ; Shaker, M. ; Szajewska, H. ; Venter, C. ; Warren, C. ; Winders, T. ; Ebisawa, M. ; Fiocchi, A. ; Monge Ortega, O. P. ; Rodriguez del Rio, P. |
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Zeitschrift: | THE WORLD ALLERGY ORGANIZATION JOURNAL, 2023, Heft 3, S. 100753 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
DOI: | 10.1016/j.waojou.2023.100753 |
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