Vandens užterštumas geležimi ir manganu bei kiti rizikos veiksniai ir įgimtos širdies ydos ; Iron and Manganese in Water and Other Risk Factors and Risk of Congenital Hearth Malformations ; Влияние загрязнения воды железом и марганцем, а также других факторов риска на раз- витие врожденных аномалий сердца

The article analyses if iron and manganese in water and other environmental factors are associated with the risk of congenital heart malformations (CHM). The investigations were based on the data received from the corresponding institutions in Kaunas. A validated CHM register and a case-control study were used to obtain data on potential CHM risk factors and to assess their effect. The results showed that water contamination with iron and manganese tended to increase the risk of CHM. The risk of CHM was associated with maternal smoking (OR = 1.98; 95 % CI 1.33–2.98) chemicals in maternal work (OR = 1.58; 95 % CI 0.92–2.72), intensive traffic and noise (OR = 1.23; 95 % CI 0.84–1.81), maternal age at delivery (OR = 1.21; 95 % CI 0.77–1.90) and marital status (OR = 1.49; 95 % CI 0.87–2.56). The risk was found to increase with the increasing number of factors present at the same time.