CMOS integrated circuit and system design for ion-sensitive FET-based biosensor applications
In: Biocybernetics and Biomedical Engineering
Online
serialPeriodical
Zugriff:
This paper presents a study on various CMOS circuit and system design techniques for ISFET-based biosensor applications including H(+) sensing and hand-held pH meter irnplementation. Based on constant-current and constant-voltage (CCCV) techniques, the conventional floating gate and bridge type floating source testing configurations for H(+) sensing have been compared. Low voltage (1.5 V /3 V /5 V) analog front-end readout circuits for ISFET sensors and the succeeding dual-slope A/D converter have been fabricated in a 0.5 žm double-poly and double-metal CMOS technology. For hand-held pH meter implementation, digital processing modules have been realized by using on-chip digital control circuits and a single-chip 89C51 controller. The key functions of digital processing contain two-point calibration, code converter and LCD display driver. Measurements have been shown that low voltage CMOS circuits present acceptable performance including linearity and flexibility for ISFET-based pH sensing system applications.
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CMOS integrated circuit and system design for ion-sensitive FET-based biosensor applications
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Autor/in / Beteiligte Person: | Chung, D. W. Y. ; Pijanowska, D.G. ; Torbicz, W. ; Wang, P. C. ; Lin, H. S. ; Hsieh, J. ; Dong, G. L. ; You, M. Y. |
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Zeitschrift: | Biocybernetics and Biomedical Engineering |
Medientyp: | serialPeriodical |
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