Simultaneous ERP and event-related fMRI: Focus on the time course of brain activity in target detection

MULERT, C ; JÄGER, L ; et al.

In: 12th Meeting of the International Pharmaco-EEG-GroupMethods and findings in experimental and clinical pharmacology 24:17-20; Jg. 24 (2002) S. 17-20

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The event-related P300 potential has been widely used in neurophysiological research. It is usually evoked with an oddball paradigm. One main reason for its broad application in neurophysiological research is the fact that in several brain/mental diseases, such as Alzheimer's disease or schizophrenia, attenuations of the P300 amplitude and latency have been described. However, a precise correlation of the scalp data to the underlying brain regions was not possible, as the correct localization of the generators of scalp-measured electroencephalogram (EEG) data was limited, due to the low spatial resolution of EEG-data. With the availability of modern imaging technologies, functional Magnetic Resonance Imaging (fMRI) in particular, the widerlying brain activations could he detected using an oddball task. Although the spatial resolution of fMRI is excellent, the time resolution is restricted. For a comprehensive understanding of the brain activity underlying the P300 paradigm, we have used a combination of EEG and fMRI to get a precise localisation and a high-time resolution of the underlying brain activity.

Titel:	Simultaneous ERP and event-related fMRI: Focus on the time course of brain activity in target detection
Autor/in / Beteiligte Person:	MULERT, C ; JÄGER, L ; POGARELL, O ; BUSSFELD, P ; SCHMITT, R ; JUCKEL, G ; HEGERL, U
Link:	Full Text Finder (Volltext) View record from PASCAL Archive
Quelle:	12th Meeting of the International Pharmaco-EEG-GroupMethods and findings in experimental and clinical pharmacology 24:17-20; Jg. 24 (2002) S. 17-20
Veröffentlichung:	Barcelona: Prous, 2002
Medientyp:	Konferenz
Umfang:	print, 10 ref SUPD
ISSN:	0379-0355 (print)
Schlagwort:	Pharmacology drugs Pharmacologie, galénique Sciences biologiques et medicales Biological and medical sciences Sciences medicales Medical sciences Techniques d'exploration et de diagnostic (generalites) Investigative techniques, diagnostic techniques (general aspects) Radiodiagnostic. Imagerie rmn. Spectrométrie rmn Radiodiagnosis. Nmr imagery. Nmr spectrometry Système nerveux Nervous system Electrodiagnostic. Enregistrement des activités électriques Electrodiagnosis. Electric activity recording Electrodiagnostic Electrodiagnosis Electrodiagnóstico Imagerie médicale Medical imagery Imaginería médica Sistema nervioso Electroencéphalographie Electroencephalography Electroencefalografía Encéphale Brain (vertebrata) Encéfalo Homme Human Hombre Imagerie RMN Nuclear magnetic resonance imaging Imaginería RMN Imagerie fonctionnelle Functional imaging Imaginería funcional Individu sain Healthy subject Individuo sano Potentiel évoqué auditif Auditory evoked potential Potencial evocado auditivo Système nerveux central Central nervous system Sistema nervioso central Technique associée Associated technique Técnica asociada
Sonstiges:	Nachgewiesen in: PASCAL Archive Sprachen: English Original Material: INIST-CNRS Document Type: Conference Paper File Description: text Language: English Author Affiliations: Laboratory for Clinical Neurophysiology, Department of Psychiatry, LMU, Munich, Germany ; Institute for Clinical Radiology, LMU, Munich, Germany Rights: Copyright 2003 INIST-CNRS ; CC BY 4.0 ; Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS Notes: Scanning and diagnostic techniques (generalities)

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