Efficacy of a vitamin A-fortified wheat-flour bun on the vitamin A status of filipino schoolchildren
In: Advances in Nutrition Education for Medical Students. SymposiumThe American journal of clinical nutrition 72(3):738-744; Jg. 72 (2000) 3, S. 738-744
Online
Konferenz
- print, 22 ref
Zugriff:
Background: Wheat flour is a possible food vehicle for vitamin A fortification. Objective: This study assessed the efficacy of consumption of a vitamin A-fortified wheat-flour bun (pandesal) on the vitamin A status of school-age children. Design: This was a double-masked clinical trial conducted in 396 and 439 children aged 6-13 y attending 4 rural schools in the Philippines. The children were randomly assigned to a vitamin A-fortified (experimental) or nonfortified (control) group. A 60-g vitamin A-fortified pandesal (containing 133 μg retinol equivalents) or a non fortified pandesal was consumed by the children 5 d/wk for 30 wk. Vitamin A status, hemoglobin concentration, anthropometric status, morbidity, and dietary intake were assessed at baseline and 30 wk later. A modified relative dose response (MRDR) was assessed in a subsample of 20% of the children (75/group) with the lowest initial serum retinol concentration at the 30-wk follow-up. Results: Baseline serum retinol significantly modified the effect of the intervention. The fortified group, whose initial serum retinol concentrations were below the median, had a 0.07 ± 0.03-μmol/L greater improvement in serum retinol at the 30-wk follow-up than did the control group (P = 0.02). Improved vitamin A status was also evident in the MRDR subsample. End-of-study differences in the MRDR showed that vitamin A-fortified pandesal intake decreased the percentage of children with inadequate liver vitamin A stores by 50% (15.3% compared with 28.6%; P = 0.05). Conclusions: Daily consumption of vitamin A-fortified pandesal significantly improved the vitamin A status of Filipino school-age children with marginal-to-low initial serum retinol concentrations.
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Efficacy of a vitamin A-fortified wheat-flour bun on the vitamin A status of filipino schoolchildren
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Autor/in / Beteiligte Person: | SOLON, Florentino S ; KLEMM, Rolf D. W ; SANCHEZ, Liza ; DARNTON-HILL, Ian ; CRAFT, Neal E ; CHRISTIAN, Parul ; WEST, Keith P |
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Quelle: | Advances in Nutrition Education for Medical Students. SymposiumThe American journal of clinical nutrition 72(3):738-744; Jg. 72 (2000) 3, S. 738-744 |
Veröffentlichung: | Bethesda, MD: American Society for Clinical Nutrition, 2000 |
Medientyp: | Konferenz |
Umfang: | print, 22 ref |
ISSN: | 0002-9165 (print) |
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