The effects of n-3 polyunsaturated fatty acids by gavage on some metabolic enzymes of rat lier

YILMAZ, H. Ramazan ; SONGUR, Ahmet ; et al.

In: Prostaglandins, leukotrienes and essential fatty acids, Jg. 71 (2004), Heft 2, S. 131-135

academicJournal - print, 36 ref

In this experimental study, the effect of fish n-3 fatty acids was studied on the some important enzymes of carbohydrate metabolism, hexokinase (HK), glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGD), lactate dehydrogenase (LDH), and malate dehydrogenase (MDH) in rat liver. Wistar albino rats of experimental group (n=9) were supplemented fish omega-3 fatty acids (n-3 PUFA) as 0.4 g/kg bw. by gavage for 30 days in addition to their normal diet. Isotonic solution was given to the control group (n = 8) by the same way. At 30th day, the rats were killed by decapitation under ether anesthesia, autopsied and liver was removed. Spectrophotometric methods were used to determine the activities of above-mentioned enzymes in the liver. The n-3 PUFA caused increases in the activities of HK, G6PD, LDH, and MDH in comparison with control. These increases were statistically significant (P<0.01) except 6PGD activity. As a result, n-3 PUFA may regulate the metabolic function of liver effectively by increasing HK, G6PD, 6PGD, LDH, and MDH enzyme activities of rat liver when added in enough amounts to the regular diet.

Titel:	The effects of n-3 polyunsaturated fatty acids by gavage on some metabolic enzymes of rat lier
Autor/in / Beteiligte Person:	YILMAZ, H. Ramazan ; SONGUR, Ahmet ; ÖZYURT, Birsen ; ZARARSIZ, Ismail ; SARSILMAZ, Mustafa
Link:	View record from PASCAL Archive
Zeitschrift:	Prostaglandins, leukotrienes and essential fatty acids, Jg. 71 (2004), Heft 2, S. 131-135
Veröffentlichung:	Kidlington: Elsevier, 2004
Medientyp:	academicJournal
Umfang:	print, 36 ref
ISSN:	0952-3278 (print)
Schlagwort:	Endocrinology Endocrinologie Hematology Hématologie Nutrition, obesity, metabolic disorders Nutrition, obésité, maladies métaboliques Physiology, morphology Physiologie, morphologie Sciences biologiques et medicales Biological and medical sciences Sciences biologiques fondamentales et appliquees. Psychologie Fundamental and applied biological sciences. Psychology Vertebres: endocrinologie Vertebrates: endocrinology Lipide Lipids Lípido Mammalia Rodentia Vertebrata Acide gras polyinsaturé Polyunsaturated fatty acid Acido graso poliinsaturado Animal Enzyme Enzima Métabolisme Metabolism Metabolismo Rat Rata Voie orale Oral administration Vía oral
Sonstiges:	Nachgewiesen in: PASCAL Archive Sprachen: English Original Material: INIST-CNRS Document Type: Article File Description: text Language: English Author Affiliations: Department of Medical Biology and Genetics, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey ; Department of Anatomy, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey ; Department of Anatomy, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey ; Department of Anatomy, Faculty of Medicine, Firat University, Elazig, Turkey Rights: Copyright 2004 INIST-CNRS ; CC BY 4.0 ; Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS Notes: Vertebrates : endocrinology

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