Leucopyrokinin (LPK) analog [D-Ala5]-[2-8]-LPK inhibits LPK-induced analgesia in rats
In: Peptides (New York, NY. 1980), Jg. 25 (2004), Heft 6, S. 1005-1011
academicJournal
- print, 10 ref
Zugriff:
It has been previously found in our laboratory that insect neuropeptide leucopyrokinin and [2-8]-leucopyrokinin, a truncated analog without the first aminoacid of leucopyrokinin peptide chain exert an antinociceptive effect in rats. The present study confirmed our previous results, and moreover it has been found that [D-Ala5]-[2-8]-leucopyrokinin, an analog of leucopyrokinin antagonized the antinociceptive effect of leucopyrokinin and of [2-8]-leucopyrokinin. We conclude that this synthetic analog is a probable leucopyrokinin antagonist.
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Leucopyrokinin (LPK) analog [D-Ala5]-[2-8]-LPK inhibits LPK-induced analgesia in rats
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Autor/in / Beteiligte Person: | PLECH, Andrzej ; RYKACZEWSKA-CZERWINSKA, Monika ; KONOPINSKA, Danuta |
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Zeitschrift: | Peptides (New York, NY. 1980), Jg. 25 (2004), Heft 6, S. 1005-1011 |
Veröffentlichung: | New York, NY: Elsevier Science, 2004 |
Medientyp: | academicJournal |
Umfang: | print, 10 ref |
ISSN: | 0196-9781 (print) |
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