Liver toxicity of lopinavir-containing regimens in HIV-infected patients with or without hepatitis C coinfection
In: AIDS research and human retroviruses, Jg. 20 (2004), Heft 7, S. 698-700
academicJournal
- print, 23 ref
Zugriff:
Liver toxicity is a common side effect of antiretroviral therapy, particularly in subjects coinfected with the hepatitis C virus (HCV). The incidence of severe liver toxicity after initiation of treatment with lopinavir (LPV) as well as its possible association with LPV plasma levels were assessed in 120 HIV-infected patients (52% coinfected by HCV). The incidence of severe liver toxicity at 3 months was 1.7% and the cumulative incidence at 12 months was 4%. The development of severe liver toxicity was associated with HCV coinfection but not with LPV plasma levels.
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Liver toxicity of lopinavir-containing regimens in HIV-infected patients with or without hepatitis C coinfection
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Autor/in / Beteiligte Person: | GONZALEZ-REQUENA MARINA NUNEZ, Daniel ; JIMENEZ-NACHER, Inmaculada ; GONZALEZ-LAHOZ, Juan ; SORIANO, Vincent |
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Zeitschrift: | AIDS research and human retroviruses, Jg. 20 (2004), Heft 7, S. 698-700 |
Veröffentlichung: | Larchmont, NY: Liebert, 2004 |
Medientyp: | academicJournal |
Umfang: | print, 23 ref |
ISSN: | 0889-2229 (print) |
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