Primary central nervous system lymphomas (PCNSL) : MRI features at presentation in 100 patients
In: Journal of neuro-oncology, Jg. 72 (2005), Heft 2, S. 169-177
Online
academicJournal
- print, 26 ref
Zugriff:
To avoid an unnecessary extend of surgery in primary central nervous system lymphoma (PCNSL), the diagnosis should be suspected after MRI. Pre-treatment MRI examinations of 100 immunologically competent patients with biopsy-proven PCNSL were evaluated. All patients had T2- and Tl-weighted images with contrast enhancement. Diffusion-weighted MRI (DW-MRI) was available in 15, proton-MR-spectroscopy (1H-MRS) in four patients. The number of lesions ranged from one (n = 65 patients) to eight (n = 1) with a mean of 1.7. The most frequent locations were the cerebral hemispheres (n = 66), the basal ganglia (n = 27) and the corpus callosum (n = 24). In the 65 patients with a solitary lesion, hemispheric lesions were most frequent (n = 23) followed by corpus callosum (n = 18). Contrast enhancement was found in all but one patient. 1H-MRS revealed a uniformly pathologic pattern of metabolite concentrations in all patients. Characteristic imaging features of PCNSL are contrast-enhancing lesions with a diameter of at least 15 mm in contact with the subarachnoid space. DW-MRI and proton spectroscopy may aid in differential diagnosis.
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Primary central nervous system lymphomas (PCNSL) : MRI features at presentation in 100 patients
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Autor/in / Beteiligte Person: | KÜKER, Wilhelm ; NÄGELE, Thomas ; KORFEL, Agnieska ; HECKL, Stefan ; THIEL, Eckhard ; BAMBERG, Michael ; WELLER, Michael ; HERRLINGER, Ulrich |
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Zeitschrift: | Journal of neuro-oncology, Jg. 72 (2005), Heft 2, S. 169-177 |
Veröffentlichung: | Dordrecht: Springer, 2005 |
Medientyp: | academicJournal |
Umfang: | print, 26 ref |
ISSN: | 0167-594X (print) |
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