Characterization of a long terminal repeat region from an infectious indian HIV type 2 isolate
In: AIDS research and human retroviruses, Jg. 21 (2005), Heft 6, S. 592-596
academicJournal
- print, 15 ref
Zugriff:
An infectious Indian human immunodeficiency virus type 2 isolate from Mumbai, propagated in this laboratory, was found to bear an unusually short long terminal repeat (LTR) region. Complete sequencing of the 601 bp LTR indicated a loss of around 250 nucleotide pairs from the unique 3' (U3) region as compared to other well-characterized HIV-2 isolates. Phylogenetic analysis of this LTR shows closest relatedness to the Guinea-Bissau subtype A isolates HIV-2CAM2 and HIV-2ALI. The LTR from the biologically active infectious clone with the observed deletion contained all functionally relevant promoter and polyadenylation sequences.
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Characterization of a long terminal repeat region from an infectious indian HIV type 2 isolate
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Autor/in / Beteiligte Person: | TAMHANE, Mayur ; MUKHOPADHYAYA, Rita ; MUKHOPADHYAYA, Robin |
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Zeitschrift: | AIDS research and human retroviruses, Jg. 21 (2005), Heft 6, S. 592-596 |
Veröffentlichung: | Larchmont, NY: Liebert, 2005 |
Medientyp: | academicJournal |
Umfang: | print, 15 ref |
ISSN: | 0889-2229 (print) |
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