Outcomes of newly diagnosed idiopathic generalized epilepsy syndromes in a non-pediatric setting
In: Acta neurologica scandinavica, Jg. 115 (2007), Heft 3, S. 204-208
Online
academicJournal
- print, 28 ref
Zugriff:
Introduction - The prognosis of idiopathic generalized epilepsy syndromes (IGES) in the adult setting may vary from that in children owing to differences in genetic, environmental and lifestyle factors. Methods - All patients diagnosed with epilepsy at the Epilepsy Unit, Western Infirmary, Glasgow, between 1981 and 2001 were reviewed. Results - Of 890 patients, 118 (13%) met the criteria for IGES. Outcomes were known for 103, 66 (64%) of whom achieved remission. The responder rate with sodium valproate was superior (66% vs 45%, P = 0.073) to that with lamotrigine (LTG) particularly in patients with juvenile myoclonic epilepsies (75% vs 39%, P = 0.014). History of febrile seizures was the only factor associated with reduced likelihood of remission (P = 0.032) Conclusions - Idiopathic generalized epilepsy syndromes constituted 13% of cases in a largely adult cohort of newly diagnosed epilepsy, most of whom achieved remission usually with a single antiepileptic drug. History of febrile seizures was associated with a poorer outcome.
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Outcomes of newly diagnosed idiopathic generalized epilepsy syndromes in a non-pediatric setting
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Autor/in / Beteiligte Person: | MOHANRAJ, R ; BRODIE, M. J |
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Zeitschrift: | Acta neurologica scandinavica, Jg. 115 (2007), Heft 3, S. 204-208 |
Veröffentlichung: | Oxford: Blackwell, 2007 |
Medientyp: | academicJournal |
Umfang: | print, 28 ref |
ISSN: | 0001-6314 (print) |
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