Up regulation of the Epstein-Barr virus (EBV)-encoded membrane protein LMP in the Burkitt's lymphoma line Daudi after exposure to n-butyrate and after EBV superinfection
In: Journal of virology, Jg. 64 (1990), Heft 11, S. 5441-5447
Online
academicJournal
- print, 48 ref
Zugriff:
We show that LMP expression can be up regulated by exposure to n-butyrate and by superinfection with the B95-8 (B virus)- and P3HR1 (P virus)-derived EBV srains. Two LMP polypeptides of 60 and 48 kilodaltons (kDa) were detected in immunoblots of Daudi cells that had been exposed to 3 mM n-butyrate for 24 h. The intensity of the 48-kDa LMP increased during 72 h, in parallel with the appearance of early antigen-positive cells. The 60-kDa LMP was expressed at a low level and remained constant. Superinfection of Daudi cells with B and P virus induced the 60-kDa LMP within 3 h.
Titel: |
Up regulation of the Epstein-Barr virus (EBV)-encoded membrane protein LMP in the Burkitt's lymphoma line Daudi after exposure to n-butyrate and after EBV superinfection
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Autor/in / Beteiligte Person: | CONTRERAS-SALAZAR, B ; EHLIN-HENRIKSSON, B ; KLEIN, G ; MASUCCI, M. G |
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Zeitschrift: | Journal of virology, Jg. 64 (1990), Heft 11, S. 5441-5447 |
Veröffentlichung: | Washington, DC: American Society for Microbiology, 1990 |
Medientyp: | academicJournal |
Umfang: | print, 48 ref |
ISSN: | 0022-538X (print) |
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