DNA methylation patterns of the rat gamma-glutamyl transpeptidase gene in embryonic, adult and neoplastic liver
In: Carcinogenesis (New York. Print), Jg. 12 (1991), Heft 6, S. 1035-1039
Online
academicJournal
- print, 47 ref
Zugriff:
During hepatocarcinogenesis, there is a modification of the DNA methylation pattern of the GGT gene, but there is no simple correlation with CGT activity. In no case was the GGT gene methylation in hepato-carcinogenesis found to be equivalent to the pattern observed in fetal liver. Thus if methylation is involved in the regulation of GGT gene transcription, the mechanisms must be different in fetal liver and hepatocarcinoma.
Titel: |
DNA methylation patterns of the rat gamma-glutamyl transpeptidase gene in embryonic, adult and neoplastic liver
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Autor/in / Beteiligte Person: | JA-HYUN, BAIK ; GRIFFITHS, S ; GIUILI, G ; MANSON, M ; SIEGRIST, S ; GUELLAEN, G |
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Zeitschrift: | Carcinogenesis (New York. Print), Jg. 12 (1991), Heft 6, S. 1035-1039 |
Veröffentlichung: | Oxford: Oxford University Press, 1991 |
Medientyp: | academicJournal |
Umfang: | print, 47 ref |
ISSN: | 0143-3334 (print) |
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