Structured lipid made from fish oil and medium-chain triglycerides alters tumor and host metabolism in Yoshida-sarcoma-bearing rats
In: The American journal of clinical nutrition, Jg. 53 (1991), Heft 5, S. 1177-1184
academicJournal
- print, 28 ref
Zugriff:
The effects of structured lipid composed of fish oil and medium-chain triglycerides (Fish/MCT) on tumor and the host metabolism was compared with conventional long-chain triglycerides (LCTs) in Yoshida-sarcoma-bearing rats receiving TPN for 3 d. The two parenterally fed groups were divided into two treatments, saline or tumor necrosis factor (TNF), given intravenously at 20 μg/kg body wt. Changes in tumor volume, body weight, urinary nitrogen, whole-body and tissue protein kinetics, and fatty acid composition were measured. The study revealed that Fish/MCT feeding inhibited tumor growth, which could be attributed to decreased tumor protein synthesis. Body weight and nitrogen were better maintained by Fish/MCT feeding.
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Structured lipid made from fish oil and medium-chain triglycerides alters tumor and host metabolism in Yoshida-sarcoma-bearing rats
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Autor/in / Beteiligte Person: | PEI RA, LING ; ISTFAN, N. W ; LOPES, S. M ; BABAYAN, V. K ; BLACKBURN, G. L ; BISTRIAN, B. R |
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Zeitschrift: | The American journal of clinical nutrition, Jg. 53 (1991), Heft 5, S. 1177-1184 |
Veröffentlichung: | Bethesda, MD: American Society for Clinical Nutrition, 1991 |
Medientyp: | academicJournal |
Umfang: | print, 28 ref |
ISSN: | 0002-9165 (print) |
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