Peripheral multifocal chorioretinitis : A distinct clinical entity?
In: Ophthalmology (Rochester, MN), Jg. 104 (1997), Heft 11, S. 1820-1826
academicJournal
- print, 20 ref
Zugriff:
Objective: The purpose of the study is to delineate the clinical features, complications, visual prognosis, and associated systemic diseases of peripheral multifocal chorioretinitis. Design: The study design was a retrospective study. Participants: Of 828 patients with uveitis, 53 patients (6.4%) fulfilled all 3 of the following criteria: (1) the presence of multiple (>10), small, round, punched-out lesions in the peripheral retina; (2) the absence of central chorioretinal lesions; and (3) an associated intraocular inflammatory reaction. Results: The majority of patients were elderly white females with bilateral ocular involvement. The presenting symptoms consisted of vitreitis and/or iritis, papillitis, and numerous retinal punched-out lesions in the periphery. On initial examination, the complications included cystoid macular edema (CME) (48%), glaucoma (25%), and cataracts (19%), resulting in a mean visual acuity of 20/80. After more than 2 years of follow-up, CME was found in 72% and cataract in 62% of the affected eyes. Submacular neovascularization never developed. The final mean visual acuity was 20/60; this was mainly dependent on the presence of CME (eyes with CME; visual acuity was 20/80, eyes without CME; visual acuity was 20/50). In 25% of patients, an association with sarcoidosis was observed (histologic and radiologic diagnoses), and an additional 29% of patients had elevated serum angiotensin-converting enzyme levels. Conclusions: Within the spectrum of multifocal chorioretinitis, the authors have defined a distinct clinical entity of peripheral multifocal chorioretinitis. The recognition of this clinical entity may be valuable because of its specific symptoms, prognosis, and association with sarcoidosis.
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Peripheral multifocal chorioretinitis : A distinct clinical entity?
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Autor/in / Beteiligte Person: | LARDENOYE, C. W. T. A ; VAN DER LELIJ, A ; DE LOOS, W. S ; TREFFERS, W. F ; ROTHOVA, A |
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Zeitschrift: | Ophthalmology (Rochester, MN), Jg. 104 (1997), Heft 11, S. 1820-1826 |
Veröffentlichung: | New York, NY: Elsevier, 1997 |
Medientyp: | academicJournal |
Umfang: | print, 20 ref |
ISSN: | 0161-6420 (print) |
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